Western Blot (WB)
(THAP11 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the THAP11 antibody detected the THAP11 protein (arrow).)
Rabbit THAP11 Polyclonal Antibody | anti-THAP11 antibody
THAP11 Antibody (N-term)
Western Blot (WB)
(THAP11 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the THAP11 antibody detected the THAP11 protein (arrow).)
Western Blot (WB)
(THAP11 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the THAP11 antibody detected the THAP11 protein (arrow).)
which is a conserved DNA-binding domain that has striking
similarity to the site-specific DNA-binding domain (DBD) of
Drosophila P element transposases.
Dejosez, M., et al. Cell 133(7):1162-1174(2008)
Roussigne, M., et al. Trends Biochem. Sci. 28(2):66-69(2003)
Ueki, N., et al. Nat. Biotechnol. 16(13):1338-1342(1998)
Li, S.H., et al. Genomics 16(3):572-579(1993)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene contains a THAP domain, which is a conserved DNA-binding domain that has striking similarity to the site-specific DNA-binding domain (DBD) of Drosophila P element transposases. [provided by RefSeq, Jul 2008]
Uniprot Description
THAP11: Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers. Belongs to the THAP11 family. Interacts (via coiled coil domain) with HCFC1.
Protein type: DNA-binding
Chromosomal Location of Human Ortholog: 16q22.1
Cellular Component: nucleoplasm; intercellular bridge; cytoplasm
Molecular Function: protein binding; DNA binding; zinc ion binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on THAP11
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Product Notes
The THAP11 thap11 (Catalog #AAA9204621) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 67-96. The THAP11 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's THAP11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the THAP11 thap11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "THAP11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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