Western Blot (WB)
(TGM6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TGM6 antibody detected the TGM6 protein (arrow).)
Rabbit anti-Human TGM6 Polyclonal Antibody | anti-TGM6 antibody
TGM6, ID (TGM6, TGM3L, Protein-glutamine gamma-glutamyltransferase 6, Transglutaminase Y, Transglutaminase-3-like, Transglutaminase-6) (Azide free) (HRP)
Gene Names
TGM6; TG6; TGY; SCA35; TGM3L; dJ734P14.3
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
TGM6; Polyclonal Antibody; ID (TGM6; TGM3L; Protein-glutamine gamma-glutamyltransferase 6; Transglutaminase Y; Transglutaminase-3-like; Transglutaminase-6) (Azide free) (HRP); Transglutaminase-6; anti-TGM6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Sequence Length
706
Applicable Applications for anti-TGM6 antibody
Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)
Application Notes
IHC: 1:50-100
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
ELISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
TGM6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 394-423 amino acids from the Central region of human TGM6.
Conjugate
HRP
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Western Blot (WB)
(TGM6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TGM6 antibody detected the TGM6 protein (arrow).)
Western Blot (WB)
(TGM6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the TGM6 antibody detected the TGM6 protein (arrow).)
Immunohistochemistry (IHC)
(TGM6 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TGM6 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TGM6 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TGM6 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(TGM6 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(TGM6 Antibody (Center) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Related Product Information for anti-TGM6 antibody
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins (By similarity).
Product Categories/Family for anti-TGM6 antibody
References
Hadjivassiliou, M., et al. Ann. Neurol. 64(3):332-343(2008). Grenard, P., et al. J. Biol. Chem. 276(35):33066-33078(2001).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase 6 isoform 1
NCBI Official Synonym Full Names
transglutaminase 6
NCBI Official Symbol
TGM6
NCBI Official Synonym Symbols
TG6; TGY; SCA35; TGM3L; dJ734P14.3
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase 6
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase 6
Protein Family
UniProt Gene Name
TGM6
UniProt Synonym Gene Names
TGM3L; TGY; TGase Y; TGase-3-like; TG6; TGase-6
UniProt Entry Name
TGM3L_HUMAN
NCBI Description
The protein encoded by this gene belongs to the transglutaminase superfamily. It catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Mutations in this gene are associated with spinocerebellar ataxia type 35 (SCA35). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Research Articles on TGM6
Similar Products
Product Notes
The TGM6 tgm6 (Catalog #AAA6355320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TGM6, ID (TGM6, TGM3L, Protein-glutamine gamma-glutamyltransferase 6, Transglutaminase Y, Transglutaminase-3-like, Transglutaminase-6) (Azide free) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TGM6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB). IHC: 1:50-100 ELISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the TGM6 tgm6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGM6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
