Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Goat TGM2/Transglutaminase 2 Polyclonal Antibody | anti-TGM2 antibody
Anti-TGM2/Transglutaminase 2 Antibody (aa667-680)
Gene Names
TGM2; TGC; TG(C)
Reactivity
HumanPredicted: Dog, Monkey
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunoaffinity Purified
Synonyms
TGM2/Transglutaminase 2; Polyclonal Antibody; Anti-TGM2/Transglutaminase 2 Antibody (aa667-680); Rabbit Polyclonal (IgG) to Human TGM2/Transglutaminase 2; TGM2; G-ALPHA-h; GNAH; TG(C); Transglutaminase 2; Transglutaminase C; TG2; TGase H; TGase-2; TGase-H; Transglutaminase H; TGase C; TGC; TTG; C polypeptide; Tgase II; Tissue transglutaminase; Transglutaminase-2; anti-TGM2 antibody
Host
Goat
Reactivity
Human
Predicted: Dog, Monkey
Predicted: Dog, Monkey
Clonality
Polyclonal
Specificity
Human TGM2/Transglutaminase 2. This antibody is expected to recognise isoform a (NP_004604.2) only.
Purity/Purification
Immunoaffinity Purified
Form/Format
Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Sequence Length
687
Applicable Applications for anti-TGM2 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
ELISA: 1:128000
IHC-P: 5-10 ug/ml
WB: 1:128000, 0.03-0.1 ug/ml
IHC-P: 5-10 ug/ml
WB: 1:128000, 0.03-0.1 ug/ml
Immunogen
Synthetic peptide C-NFESDKLKAVKGFR from an internal region (near the C-terminus) of human TGM2/Transglutaminase 2 (NP_004604.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Marmoset, Panda, Dog (100%); Bovine, Rabbit (93%); Elephant, Guinea pig, Xenopus (86%).
Conjugation
Unconjugated
Epitope
aa667-680
Preparation and Storage
Store at -20 degree C.
Avoid freeze-thaw cycles.
Avoid freeze-thaw cycles.
Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Immunohistochemistry (IHC)
(Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE))
Western Blot (WB)
(Antibody (0.03 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
(Antibody (0.03 ug/ml) staining of Human Lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Related Product Information for anti-TGM2 antibody
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all havethe same amino acid sequence at their active sites and their activity iscalcium-dependent. the protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis.Finally, the encoded protein is the autoantigen implicated in celiacdisease.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
38,671 Da
NCBI Official Full Name
protein-glutamine gamma-glutamyltransferase 2 isoform a
NCBI Official Synonym Full Names
transglutaminase 2
NCBI Official Symbol
TGM2
NCBI Official Synonym Symbols
TGC; TG(C)
NCBI Protein Information
protein-glutamine gamma-glutamyltransferase 2
UniProt Protein Name
Protein-glutamine gamma-glutamyltransferase 2
Protein Family
UniProt Gene Name
TGM2
UniProt Synonym Gene Names
TG(C); TGC; TGase C; TGase H; TGase-2
NCBI Description
Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon-gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Uniprot Description
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
Research Articles on TGM2
Similar Products
Product Notes
The TGM2 tgm2 (Catalog #AAA2401300) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Anti-TGM2/Transglutaminase 2 Antibody (aa667-680) reacts with Human Predicted: Dog, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's TGM2/Transglutaminase 2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). ELISA: 1:128000 IHC-P: 5-10 ug/ml WB: 1:128000, 0.03-0.1 ug/ml. Researchers should empirically determine the suitability of the TGM2 tgm2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TGM2/Transglutaminase 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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