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Rabbit Tgfb3 Polyclonal Antibody | anti-Tgfb3 antibody

Tgfb3 antibody

Gene Names
TGFB3; ARVD; RNHF; ARVD1; TGF-beta3
Applications
Western Blot
Synonyms
Tgfb3; Polyclonal Antibody; Tgfb3 antibody; Polyclonal Tgfb3; Anti-Tgfb3; Tgfb 3; Tgfb-3; transforming growth factor; MGC105479; beta 3; anti-Tgfb3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Clonality
Polyclonal
Form/Format
Lyophilized powder. Add 50 ul of distilled water. Final antibody concentration is 1 mg/ml in PBS buffer.
Concentration
1 mg/ml (varies by lot)
Sequence Length
412
Applicable Applications for anti-Tgfb3 antibody
Western Blot (WB)
Application Notes
Optimal conditions to be determined by the end user
Biological Significance
Tgfb3 is involved in epithelial and endothelial cell proliferation and differentiation during development.
Cross-Reactivity
Human, Rat
Immunogen
Tgfb3 antibody was raised in rabbit using the middle region of Tgfb3 as the immunogen
Preparation and Storage
Store at 4 degree C, following reconstitution, aliquot and store at -20 degree C. Avoid repeated freeze-thaw cycles.
Related Product Information for anti-Tgfb3 antibody
Affinity purified rabbit polyclonal Tgfb3 antibody
Product Categories/Family for anti-Tgfb3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,708 Da
NCBI Official Full Name
transforming growth factor beta-3 preproprotein
NCBI Official Synonym Full Names
transforming growth factor, beta 3
NCBI Official Symbol
TGFB3
NCBI Official Synonym Symbols
ARVD; RNHF; ARVD1; TGF-beta3
NCBI Protein Information
transforming growth factor beta-3
UniProt Protein Name
Transforming growth factor beta-3
UniProt Gene Name
TGFB3
UniProt Synonym Gene Names
TGF-beta-3; LAP
UniProt Entry Name
TGFB3_HUMAN

NCBI Description

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and is involved in embryogenesis and cell differentiation. Defects in this gene are a cause of familial arrhythmogenic right ventricular dysplasia 1. [provided by RefSeq, Mar 2009]

Uniprot Description

TGFB3: Involved in embryogenesis and cell differentiation. Homodimer; disulfide-linked. Interacts with ASPN. Belongs to the TGF-beta family.

Protein type: Cell development/differentiation; Secreted; Secreted, signal peptide; Ligand, receptor tyrosine kinase; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q24

Cellular Component: extracellular matrix; extracellular space; cell surface; cell soma; T-tubule; plasma membrane; extracellular region; nucleus

Molecular Function: identical protein binding; protein binding; growth factor activity; protein heterodimerization activity; transforming growth factor beta binding; punt binding; cytokine activity

Biological Process: extracellular matrix organization and biogenesis; activation of MAPK activity; positive regulation of apoptosis; positive regulation of transcription, DNA-dependent; positive regulation of collagen biosynthetic process; female pregnancy; SMAD protein nuclear translocation; palate development; odontogenesis; regulation of apoptosis; negative regulation of cell proliferation; platelet degranulation; mammary gland development; transforming growth factor beta receptor signaling pathway; salivary gland morphogenesis; embryonic neurocranium morphogenesis; negative regulation of neuron apoptosis; cell growth; inner ear development; aging; uterine wall breakdown; positive regulation of filopodium formation; platelet activation; intercellular junction assembly and maintenance; in utero embryonic development; positive regulation of bone mineralization; regulation of cell proliferation; gut development; positive regulation of protein secretion; negative regulation of DNA replication; response to estrogen stimulus; regulation of MAPKKK cascade; positive regulation of cell division; response to hypoxia; positive regulation of transcription from RNA polymerase II promoter; response to progesterone stimulus; blood coagulation; negative regulation of transforming growth factor beta receptor signaling pathway; alveolus development; positive regulation of DNA replication

Disease: Arrhythmogenic Right Ventricular Dysplasia, Familial, 1; Rienhoff Syndrome

Research Articles on Tgfb3

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Product Notes

The Tgfb3 tgfb3 (Catalog #AAA5300051) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Tgfb3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Optimal conditions to be determined by the end user. Researchers should empirically determine the suitability of the Tgfb3 tgfb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tgfb3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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