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Immunofluorescence (IF) (Immunofluorescence analysis of U2OS cell using TFPT antibody.)

Rabbit TFPT Polyclonal Antibody | anti-TFPT antibody

TFPT antibody

Gene Names
TFPT; FB1; amida; INO80F
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunofluorescence
Purity
Antibodies were purified by affinity purification using immunogen.
Synonyms
TFPT; Polyclonal Antibody; TFPT antibody; FB1; amida; INO80F; anti-TFPT antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
The antibody detects endogenous level of total TFPT antibody.
Purity/Purification
Antibodies were purified by affinity purification using immunogen.
Form/Format
Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
253
Applicable Applications for anti-TFPT antibody
Western Blot (WB), Immunofluorescence (IF)
Application Notes
Western blotting: 1:500 - 1:2000
Immunofluorescence: 1:50 - 1:100
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant protein of human TFPT.
Target Name
TFPT
Preparation and Storage
Store at -20 degree C

Immunofluorescence (IF)

(Immunofluorescence analysis of U2OS cell using TFPT antibody.)

Immunofluorescence (IF) (Immunofluorescence analysis of U2OS cell using TFPT antibody.)
Related Product Information for anti-TFPT antibody
Appears to promote apoptosis in a p53/TP53-independent manner.
Product Categories/Family for anti-TFPT antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,278 Da
NCBI Official Full Name
TCF3 fusion partner
NCBI Official Synonym Full Names
TCF3 (E2A) fusion partner (in childhood Leukemia)
NCBI Official Symbol
TFPT
NCBI Official Synonym Symbols
FB1; amida; INO80F
NCBI Protein Information
TCF3 fusion partner
UniProt Protein Name
TCF3 fusion partner
Protein Family
UniProt Gene Name
TFPT
UniProt Synonym Gene Names
INO80F
UniProt Entry Name
TFPT_HUMAN

Uniprot Description

TFPT: forms a fusion protein with E2A via translocation in childhood pre-B ALL. Overexpression of TFPT induces apoptosis. Causes cell cycle inhibition in the S-phase and blocks entry into mitosis. Interacts with Cdc2 in mitosis and overexpression decreases Cdc2 activity.

Protein type: Apoptosis; Oncoprotein

Chromosomal Location of Human Ortholog: 19q13

Cellular Component: nucleoplasm; nuclear membrane; cytoplasm; nucleolus; actin filament; nucleus

Molecular Function: protein binding; DNA binding; protein heterodimerization activity; protein kinase binding

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of apoptosis; DNA repair; DNA recombination

Research Articles on TFPT

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Product Notes

The TFPT tfpt (Catalog #AAA9414448) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TFPT antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TFPT can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunofluorescence (IF). Western blotting: 1:500 - 1:2000 Immunofluorescence: 1:50 - 1:100. Researchers should empirically determine the suitability of the TFPT tfpt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TFPT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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