Western Blot (WB)
(Western blotAll lanes: TFCP2 antibody at 1.34ug/mlLane 1:K562 whole cell lysateLane 2:Mouse spleen tissueLane 3:Mouse kidney tissueLane 4:THP-1 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 58,52 kDaObserved band size: 57 kDa)
Rabbit anti-Human, Mouse TFCP2 Polyclonal Antibody | anti-TFCP2 antibody
TFCP2 Antibody
Western Blot (WB)
(Western blotAll lanes: TFCP2 antibody at 1.34ug/mlLane 1:K562 whole cell lysateLane 2:Mouse spleen tissueLane 3:Mouse kidney tissueLane 4:THP-1 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 58,52 kDaObserved band size: 57 kDa)
Western Blot (WB)
(Western blotAll lanes: TFCP2 antibody at 1.34ug/mlLane 1:K562 whole cell lysateLane 2:Mouse spleen tissueLane 3:Mouse kidney tissueLane 4:THP-1 whole cell lysateSecondaryGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 58,52 kDaObserved band size: 57 kDa)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7045551 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human adrenal gland tissue using MBS7045551 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human thymus tissue using MBS7045551 at dilution 1:100)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded human thymus tissue using MBS7045551 at dilution 1:100)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimer's disease. [provided by RefSeq, Mar 2010]
Uniprot Description
TFCP2: Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1. Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter. Belongs to the grh/CP2 family. CP2 subfamily. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: nucleus
Molecular Function: DNA binding; protein binding; sequence-specific DNA binding; transcription factor activity
Biological Process: regulation of transcription from RNA polymerase II promoter
Research Articles on TFCP2
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Product Notes
The TFCP2 tfcp2 (Catalog #AAA7045551) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TFCP2 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TFCP2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the TFCP2 tfcp2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TFCP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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