Rabbit anti-Human TFAP2A Polyclonal Antibody | anti-TFAP2A antibody

TFAP2A, CT (Transcription Factor AP-2-alpha, AP2-alpha, Activating Enhancer-Binding Protein 2 alpha, AP-2 Transcription Factor, Activator Protein 2, AP-2, AP2TF, TFAP2) (AP)

Cat. Num. AAA6503301

• Gene Names: TFAP2A; AP-2; BOFS; AP2TF; TFAP2; AP-2alpha
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TFAP2A; Polyclonal Antibody; CT (Transcription Factor AP-2-alpha; AP2-alpha; Activating Enhancer-Binding Protein 2 alpha; AP-2 Transcription Factor; Activator Protein 2; AP-2; AP2TF; TFAP2) (AP); anti-TFAP2A antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human TFAP2A.
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-TFAP2A antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:50-1:100; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the C-terminal region of human TFAP2A (KLH).
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: May be stored at 4 degree C for short-term only. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of TFAP2A Antibody (C-term) in NCI-H460 cell line lysates (35ug/lane). TFAP2A (arrow) was detected using the purified Pab.)

Product Categories/Family for anti-TFAP2A antibody

Antibodies; Transcription Factors

References

1. Provenzano, M.J., Exp. Mol. Pathol. 83(2), 277-282 (2007). 2. Tan, Y.R., Biochem. J. 405(1), 131-137 (2007). 3. Liu, H., EMBO Rep. 8(4), 394-400 (2007). 4. Han, S., J. Biol. Chem. 282(11), 7961-7972 (2007).

NCBI and Uniprot Product Information

• NCBI GI #: 4507441
• NCBI GeneID: 7020
• NCBI Accession #: NP_003211
• NCBI GenBank Nucleotide #: NM_003220.3
• UniProt Accession #: P05549
• Molecular Weight: 48kDa
• NCBI Official Full Name: transcription factor AP-2-alpha isoform a
• NCBI Official Synonym Full Names: transcription factor AP-2 alpha
• NCBI Official Symbol: TFAP2A
• NCBI Official Synonym Symbols: AP-2; BOFS; AP2TF; TFAP2; AP-2alpha
• NCBI Protein Information: transcription factor AP-2-alpha
• UniProt Protein Name: Transcription factor AP-2-alpha
• Protein Family: Transcription factor
• UniProt Gene Name: TFAP2A
• UniProt Synonym Gene Names: AP2TF; TFAP2; AP2-alpha; AP-2
• UniProt Entry Name: AP2A_HUMAN

NCBI Description

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]