Western Blot (WB)
(WB Suggested Anti-TESK2 AntibodyTitration: 1.0 ug/mlPositive Control: MCF7 Whole Cell)
Rabbit TESK2 Polyclonal Antibody | anti-TESK2 antibody
TESK2 Antibody - C-terminal region
Western Blot (WB)
(WB Suggested Anti-TESK2 AntibodyTitration: 1.0 ug/mlPositive Control: MCF7 Whole Cell)
Western Blot (WB)
(WB Suggested Anti-TESK2 AntibodyTitration: 1.0 ug/mlPositive Control: MCF7 Whole Cell)
Target Description: This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis.
NCBI and Uniprot Product Information
NCBI Description
This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain that is structurally similar to the kinase domains of testis-specific protein kinase-1 and the LIM motif-containing protein kinases (LIMKs). Its overall structure is most related to the former, indicating that it belongs to the TESK subgroup of the LIMK/TESK family of protein kinases. This gene is predominantly expressed in testis and prostate. The developmental expression pattern of the rat gene in testis suggests an important role for this gene in meitoic stages and/or early stages of spermiogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Uniprot Description
TESK2: a TKL kinase of the LISK family. Predominantly expressed in testis and prostate. The developmental expression pattern in the testis suggests an important role in meitoic stages and/or early stages of spermiogenesis. Three alternatively spliced isoforms have been described.
Protein type: Kinase, protein; EC 2.7.12.1; Protein kinase, Ser/Thr (non-receptor); Protein kinase, TKL; TKL group; LISK family; TESK subfamily
Chromosomal Location of Human Ortholog: 1p32
Cellular Component: nucleoplasm; cytoplasm; nucleus
Molecular Function: protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; metal ion binding; protein serine/threonine/tyrosine kinase activity; ATP binding; protein kinase activity
Biological Process: focal adhesion formation; peptidyl-tyrosine phosphorylation; spermatogenesis; actin cytoskeleton organization and biogenesis; protein amino acid phosphorylation
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Product Notes
The TESK2 tesk2 (Catalog #AAA3217208) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TESK2 Antibody - C-terminal region reacts with Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TESK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the TESK2 tesk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: AHEAMDCSIL QEENGFGSRP QGTSPCPAGA SEEMEVEERP AGSTPATFST. It is sometimes possible for the material contained within the vial of "TESK2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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