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Western Blot (WB) (HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS7604833 (TES antibody) at dilution of 1:300)

Rabbit TES Polyclonal Antibody | anti-TES antibody

TES Rabbit Polyclonal

Gene Names
TES; TESS; TESS-2
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
TES; Polyclonal Antibody; TES Rabbit Polyclonal; anti-TES antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
412
Applicable Applications for anti-TES antibody
ELISA (EIA), Western Blot (WB)
Immunogen
Testis derived transcript (3 LIM domains)
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS7604833 (TES antibody) at dilution of 1:300)

Western Blot (WB) (HEK-293 cells were subjected to SDS PAGE followed by western blot with MBS7604833 (TES antibody) at dilution of 1:300)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,910 Da
NCBI Official Full Name
testin isoform 2
NCBI Official Synonym Full Names
testin LIM domain protein
NCBI Official Symbol
TES
NCBI Official Synonym Symbols
TESS; TESS-2
NCBI Protein Information
testin
UniProt Protein Name
Testin
Protein Family
UniProt Gene Name
TES
UniProt Entry Name
TES_HUMAN

NCBI Description

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011]

Uniprot Description

TES: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. Belongs to the prickle / espinas / testin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: cell junction; cytoplasm; focal adhesion; nucleus; plasma membrane; protein complex

Molecular Function: protein binding; zinc ion binding

Biological Process: negative regulation of cell proliferation

Research Articles on TES

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Product Notes

The TES tes (Catalog #AAA7604833) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TES Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TES can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the TES tes for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TES, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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