Western Blot (WB)
(Western blot analysis of Tensin 2 (pY483) expression in A549 (A), Hela (B), NIH3T3 (C) whole cell lysates.)
Rabbit anti-Human, Mouse Tensin 2 Polyclonal Antibody | anti-TENC1 antibody
Anti-Tensin 2 (pY483) Phospho Antibody
Western Blot (WB)
(Western blot analysis of Tensin 2 (pY483) expression in A549 (A), Hela (B), NIH3T3 (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of Tensin 2 (pY483) expression in A549 (A), Hela (B), NIH3T3 (C) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
tensin 2: Regulates cell motility and proliferation. May have phosphatase activity. Reduces AKT1 phosphorylation. Lowers AKT1 kinase activity and interferes with AKT1 signaling. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.-; Cell adhesion; Cell cycle regulation; Phosphatase
Chromosomal Location of Human Ortholog: 12q13.13
Cellular Component: focal adhesion; intracellular; plasma membrane
Molecular Function: kinase binding; metal ion binding; phosphoprotein phosphatase activity; protein binding
Biological Process: cellular homeostasis; collagen metabolic process; kidney development; multicellular organism growth; multicellular organismal homeostasis; negative regulation of cell proliferation; protein amino acid dephosphorylation; response to muscle activity
Research Articles on TENC1
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Product Notes
The TENC1 tns2 (Catalog #AAA8242992) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Tensin 2 (pY483) Phospho Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Tensin 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Western Blot: (1/500 - 1/1000); Immunoprecipitation: (1/10 - 1/100). Researchers should empirically determine the suitability of the TENC1 tns2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tensin 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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