Rabbit anti-Human TCEA3 Polyclonal Antibody | anti-Tcea3 antibody

TCEA3, ID (TCEA3, TFIISH, Transcription elongation factor A protein 3, Transcription elongation factor S-II protein 3, Transcription elongation factor TFIIS.h)

Cat. Num. AAA6008737

• Gene Names: Tcea3; S-II; SII-K1
• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: TCEA3; Polyclonal Antibody; ID (TCEA3; TFIISH; Transcription elongation factor A protein 3; Transcription elongation factor S-II protein 3; Transcription elongation factor TFIIS.h); Anti -TCEA3; anti-Tcea3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-Tcea3 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: TCEA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human TCEA3.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TCEA3 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the TCEA3 antibody detected the TCEA3 protein (arrow).)

Related Product Information for anti-Tcea3 antibody

TCEA3 is necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.

Product Categories/Family for anti-Tcea3 antibody

Antibodies; Abs to Transcription Factors

NCBI and Uniprot Product Information

• NCBI GI #: 32189438
• NCBI GeneID: 21401
• NCBI Accession #: NP_035672.1
• NCBI GenBank Nucleotide #: NM_011542.2
• UniProt Accession #: P23881; O88710; Q9CTZ8; Q9DCZ5; A2AW46
• Molecular Weight: 38,850 Da
• NCBI Official Full Name: transcription elongation factor A protein 3
• NCBI Official Synonym Full Names: transcription elongation factor A (SII), 3
• NCBI Official Symbol: Tcea3
• NCBI Official Synonym Symbols: S-II; SII-K1
• NCBI Protein Information: transcription elongation factor A protein 3; transcription elongation factor TFIIS.h; tissue-specific transcription factor S-II; transcription elongation factor S-II protein 3
• UniProt Protein Name: Transcription elongation factor A protein 3
• Protein Family: Transcription elongation factor A protein
• UniProt Gene Name: Tcea3
• UniProt Synonym Gene Names: Tfiish
• UniProt Entry Name: TCEA3_MOUSE

Uniprot Description

TCEA3: Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Belongs to the TFS-II family.

Cellular Component: nucleus

Molecular Function: DNA binding; nucleic acid binding; zinc ion binding; metal ion binding

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of transcription, DNA-dependent; transcription, DNA-dependent; regulation of RNA elongation