Rabbit anti-Human, Mouse TBKB1 Polyclonal Antibody | anti-TBKB1 antibody

TBKB1, NT (TBKBP1, KIAA0775, TANK-binding kinase 1-binding protein 1) (APC)

Cat. Num. AAA6354085

• Gene Names: TBKBP1; SINTBAD; ProSAPiP2
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TBKB1; Polyclonal Antibody; NT (TBKBP1; KIAA0775; TANK-binding kinase 1-binding protein 1) (APC); TBKBP1; TANK-binding kinase 1-binding protein 1; anti-TBKB1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

• Applicable Applications for anti-TBKB1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TBKB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-80 amino acids from the N-terminal region of human TBKB1.
• Conjugate: APC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(TBKB1 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the TBKB1 antibody detected TBKB1 protein (arrow).)

Related Product Information for anti-TBKB1 antibody

TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway

Product Categories/Family for anti-TBKB1 antibody

Antibodies; Protein Kinases

References

Ryzhakov, G., et al. EMBO J. 26(13):3180-3190(2007). Kim, J.M., et al. DNA Res. 13(6):275-286(2006). Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004).

NCBI and Uniprot Product Information

• NCBI GI #: 7662302
• NCBI GeneID: 9755
• NCBI Accession #: NP_055541.1
• NCBI GenBank Nucleotide #: NM_014726.2
• UniProt Accession #: A7MCY6; O94873; Q14DW3; B2RZG6
• Molecular Weight: 25,043 Da
• NCBI Official Full Name: TANK-binding kinase 1-binding protein 1
• NCBI Official Synonym Full Names: TBK1 binding protein 1
• NCBI Official Symbol: TBKBP1
• NCBI Official Synonym Symbols: SINTBAD; ProSAPiP2
• NCBI Protein Information: TANK-binding kinase 1-binding protein 1; TBKBP1; TBK1-binding protein 1
• UniProt Protein Name: TANK-binding kinase 1-binding protein 1
• UniProt Gene Name: TBKBP1
• UniProt Synonym Gene Names: TBK1-binding protein 1
• UniProt Entry Name: TBKB1_HUMAN

NCBI Description

TBKBP1 is an adaptor protein that binds to TBK1 (MIM 604834) and is part of the interaction network in the TNF (MIM 191160)/NFKB (see MIM 164011) pathway (Bouwmeester et al., 2004 [PubMed 14743216]).[supplied by OMIM, Mar 2008]

Uniprot Description

TBKBP1: Adapter protein which constitutively binds TBK1 and IKBKE and may play a role in antiviral innate immunity. Homodimer. May form a heterodimer with NAP1. Interacts with TKB1 and IKBKE. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 17q21.32

Molecular Function: protein binding

Biological Process: innate immune response