Rabbit TAS2R50 Polyclonal Antibody | anti-TAS2R50 antibody

TAS2R50 Antibody

Cat. Num. AAA9603127

• Gene Names: TAS2R50; T2R50; T2R51; TAS2R51
• Reactivity: Human, Mouse, Rat
• Applications: Western Blot, ELISA
• Purity: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Synonyms: TAS2R50; Polyclonal Antibody; TAS2R50 Antibody; T2R50; T2R50_HUMAN; T2R51; Taste receptor type 2 member 50; Taste receptor type 2 member 51; anti-TAS2R50 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: TAS2R50 antibody detects endogenous levels of total TAS2R50
• Purity/Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
• Form/Format: Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: 1mg/ml (varies by lot)
• Sequence Length: 299

• Applicable Applications for anti-TAS2R50 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:1000-3000
• Immunogen: A synthesized peptide derived from human TAS2R50
• Tissue Specificity: Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot analysis of TAS2R50 using HeLa whole cell lysates)

Related Product Information for anti-TAS2R50 antibody

Function: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
Similarity: Belongs to the G-protein coupled receptor T2R family.

NCBI and Uniprot Product Information

• NCBI GI #: 154937357
• NCBI GeneID: 259296
• NCBI Accession #: NP_795371.2
• NCBI GenBank Nucleotide #: NM_176890.2
• UniProt Accession #: P59544; P59545; Q2M255; Q645Y0
• Molecular Weight: Observed: 35 kDa; Predicted: 35 kDa
• NCBI Official Full Name: taste receptor type 2 member 50
• NCBI Official Synonym Full Names: taste 2 receptor member 50
• NCBI Official Symbol: TAS2R50
• NCBI Official Synonym Symbols: T2R50; T2R51; TAS2R51
• NCBI Protein Information: taste receptor type 2 member 50
• UniProt Protein Name: Taste receptor type 2 member 50
• Protein Family: Taste receptor
• UniProt Gene Name: TAS2R50
• UniProt Synonym Gene Names: T2R50; T2R51

NCBI Description

TAS2R50 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). See also TAS2R10 (MIM 604791).[supplied by OMIM, Mar 2008]

Uniprot Description

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 ().