Western Blot (WB)
(TAS2R43 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).)
Rabbit anti-Human TAS2R43 Polyclonal Antibody | anti-TAS2R43 antibody
TAS2R43 Antibody (Center)
Western Blot (WB)
(TAS2R43 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).)
Western Blot (WB)
(TAS2R43 Antibody (Center) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the TAS2R43 antibody detected the TAS2R43 protein (arrow).)
NCBI and Uniprot Product Information
NCBI Description
TAS2R43 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Mar 2009]
Uniprot Description
TAS2R43: Gustducin-coupled receptor immplicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency. May act as chemosensory receptors in airway epithelial cells to detect and eliminate potential noxious agents from the airways. Belongs to the G-protein coupled receptor T2R family.
Protein type: Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral; GPCR, T2R family
Chromosomal Location of Human Ortholog: 12p13.2
Cellular Component: plasma membrane; integral to membrane
Molecular Function: bitter taste receptor activity; taste receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of bitter taste
Research Articles on TAS2R43
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Product Notes
The TAS2R43 tas2r43 (Catalog #AAA9204034) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 135-163. The TAS2R43 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAS2R43 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the TAS2R43 tas2r43 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAS2R43, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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