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Dot Blot (DB) (Dot Blot analysis on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed using MBS6002077 at 0.5ug per ml.)

Rabbit anti-Human TAL1 Polyclonal Antibody | anti-TAL1 antibody

TAL1, phosphorylated (pT90) (TAL1, BHLHA17, SCL, TCL5, T-cell acute lymphocytic leukemia protein 1, Class A basic helix-loop-helix protein 17, Stem cell protein, T-cell leukemia/lymphoma protein 5)

Gene Names
TAL1; SCL; TCL5; tal-1; bHLHa17
Reactivity
Human
Applications
ELISA, Gel Super Shift Assay
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
TAL1; Polyclonal Antibody; phosphorylated (pT90) (TAL1; BHLHA17; SCL; TCL5; T-cell acute lymphocytic leukemia protein 1; Class A basic helix-loop-helix protein 17; Stem cell protein; T-cell leukemia/lymphoma protein 5); Anti -TAL1; anti-TAL1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-TAL1 antibody
ELISA (EL/EIA), Gel Shift Assay (GS/EMSA)
Application Notes
Suitable for use in Dot Blot, ELISA
Dilution: ELISA: 1:1,000
Dot Blot 1:500
Immunogen
Phospho-TAL1-pT90 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 75~105 amino acids surrounding pT90 of human TAL1.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Dot Blot (DB)

(Dot Blot analysis on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed using MBS6002077 at 0.5ug per ml.)

Dot Blot (DB) (Dot Blot analysis on nitrocellulose membrane. 50ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed using MBS6002077 at 0.5ug per ml.)
Related Product Information for anti-TAL1 antibody
TAL1 is implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation and serves as a positive regulator of erythroid differentiation.
Product Categories/Family for anti-TAL1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,271 Da
NCBI Official Full Name
T-cell acute lymphocytic leukemia protein 1
NCBI Official Synonym Full Names
T-cell acute lymphocytic leukemia 1
NCBI Official Symbol
TAL1
NCBI Official Synonym Symbols
SCL; TCL5; tal-1; bHLHa17
NCBI Protein Information
T-cell acute lymphocytic leukemia protein 1; tal-1 product; stem cell protein; T-cell leukemia/lymphoma protein 5; class A basic helix-loop-helix protein 17
UniProt Protein Name
T-cell acute lymphocytic leukemia protein 1
Protein Family
UniProt Gene Name
TAL1
UniProt Synonym Gene Names
BHLHA17; SCL; TCL5; TAL-1; bHLHa17
UniProt Entry Name
TAL1_HUMAN

Uniprot Description

TAL1: a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2.

Protein type: Transcription factor; DNA-binding; Oncoprotein

Chromosomal Location of Human Ortholog: 1p32

Cellular Component: transcription factor complex; nuclear chromatin; histone deacetylase complex; nucleus

Molecular Function: protein binding; enzyme binding; protein heterodimerization activity; histone deacetylase binding; chromatin binding; transcription factor activity

Biological Process: transcription from RNA polymerase II promoter; erythrocyte maturation; cell fate commitment; positive regulation of chromatin assembly or disassembly; megakaryocyte differentiation; embryonic hemopoiesis; positive regulation of erythrocyte differentiation; positive regulation of transcription, DNA-dependent; astrocyte fate commitment; locomotory behavior; negative regulation of transcription from RNA polymerase II promoter; positive regulation of mitotic cell cycle; regulation of cell proliferation; regulation of transcription from RNA polymerase II promoter; positive regulation of protein complex assembly; positive regulation of cell division; erythrocyte differentiation; spinal cord association neuron differentiation; hemopoiesis; positive regulation of transcription from RNA polymerase II promoter; angiogenesis; platelet formation; basophil differentiation

Disease: Leukemia, Acute Lymphoblastic

Research Articles on TAL1

Similar Products

Product Notes

The TAL1 tal1 (Catalog #AAA6002077) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TAL1, phosphorylated (pT90) (TAL1, BHLHA17, SCL, TCL5, T-cell acute lymphocytic leukemia protein 1, Class A basic helix-loop-helix protein 17, Stem cell protein, T-cell leukemia/lymphoma protein 5) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAL1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Gel Shift Assay (GS/EMSA). Suitable for use in Dot Blot, ELISA Dilution: ELISA: 1:1,000 Dot Blot 1:500. Researchers should empirically determine the suitability of the TAL1 tal1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAL1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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