Rabbit anti-Human, Mouse TAGLN3 Polyclonal Antibody | anti-TAGLN3 antibody

TAGLN3, NT (TAGLN3, NP25, Transgelin-3, Neuronal protein 22, Neuronal protein NP25) (FITC)

Cat. Num. AAA6353493

• Gene Names: TAGLN3; NP22; NP24; NP25
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: TAGLN3; Polyclonal Antibody; NT (TAGLN3; NP25; Transgelin-3; Neuronal protein 22; Neuronal protein NP25) (FITC); Neuronal protein NP25; anti-TAGLN3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-TAGLN3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: TAGLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TAGLN3.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(TAGLN3 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the TAGLN3 Antibody detected the TAGLN3 protein (arrow).)

Product Categories/Family for anti-TAGLN3 antibody

Antibodies; Neuroscience

References

Lamesch, P., et al. Genomics 89(3):307-315(2007). Ito, M., et al. Neurosci. Lett. 378(3):125-130(2005). Depaz, I., et al. Alcohol. Clin. Exp. Res. 27(9):1481-1488(2003). Wistow, G., et al. Mol. Vis. 8, 196-204 (2002): Fan, L., et al. J. Neurochem. 76(5):1275-1281(2001).

NCBI and Uniprot Product Information

• NCBI GI #: 56549137
• NCBI GeneID: 29114
• NCBI Accession #: NP_001008273.1
• NCBI GenBank Nucleotide #: NM_001008272.1
• UniProt Accession #: Q9UI15; Q96A74; D3DN64
• Molecular Weight: 22,473 Da
• NCBI Official Full Name: transgelin-3
• NCBI Official Synonym Full Names: transgelin 3
• NCBI Official Symbol: TAGLN3
• NCBI Official Synonym Symbols: NP22; NP24; NP25
• NCBI Protein Information: transgelin-3; neuronal protein 22; neuronal protein NP25
• UniProt Protein Name: Transgelin-3
• Protein Family: Transgelin
• UniProt Gene Name: TAGLN3
• UniProt Synonym Gene Names: NP25; NP22
• UniProt Entry Name: TAGL3_HUMAN

Uniprot Description

TAGLN3: a cytoskeleton-associated protein that colocalizes with microtubules and actin. Its expression rises incrementally during rat brain development, with highest expression during synaptogenesis. Its expression is altered in the frontal cortex but not the motor cortex of alcoholic human brains. Induced in rat brains during adaptation to ethanol. Contains a CH-domain and a Calponin-domain.

Protein type: Actin-binding

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: nucleus

Molecular Function: actin filament binding

Biological Process: central nervous system development; negative regulation of transcription from RNA polymerase II promoter