Western Blot (WB)
(TAGAP Antibody (Center)(MBS9202160) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TAGAP antibody detected the TAGAP protein (arrow).)
Rabbit anti-Human TAGAP Polyclonal Antibody | anti-TAGAP antibody
TAGAP Antibody (Center)
IHC-P~~1:50~100
FC~~1:10~50
Western Blot (WB)
(TAGAP Antibody (Center)(MBS9202160) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TAGAP antibody detected the TAGAP protein (arrow).)
Western Blot (WB)
(TAGAP Antibody (Center)(MBS9202160) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TAGAP antibody detected the TAGAP protein (arrow).)
Immunohistochemistry (IHC)
(TAGAP antibody (Center)(MBS9202160) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TAGAP antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(TAGAP antibody (Center)(MBS9202160) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the TAGAP antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(TAGAP Antibody (Center)(MBS9202160) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(TAGAP Antibody (Center)(MBS9202160) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
GTPase-activating protein. Transcript variants encoding distinct
isoforms have been identified.
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Amundsen, S.S., et al. Genes Immun. 11(1):79-86(2010)
Raychaudhuri, S., et al. Nat. Genet. 41(12):1313-1318(2009)
Trynka, G., et al. Gut 58(8):1078-1083(2009)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Rho GTPase-activator protein superfamily. The encoded protein may function as a Rho GTPase-activating protein. Alterations in this gene may be associated with several diseases, including rheumatoid arthritis, celiac disease, and multiple sclerosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]
Uniprot Description
TAGAP: an apparent GTPase-activating protein (GAP) for Rho monomeric G proteins. May play important roles during T-cell activation. Mutations have been associated with various autoimmune conditions including rheumatoid arthritis, Crohn¿s disease, and celiac disease. Four isoforms of the human protein are produced by alternative splicing.
Protein type: GAPs, Rac/Rho; GAPs
Chromosomal Location of Human Ortholog: 6q25.3
Cellular Component: cytosol
Molecular Function: guanyl-nucleotide exchange factor activity
Biological Process: regulation of small GTPase mediated signal transduction; small GTPase mediated signal transduction; positive regulation of GTPase activity
Research Articles on TAGAP
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Product Notes
The TAGAP tagap (Catalog #AAA9202160) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 103-129. The TAGAP Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TAGAP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50. Researchers should empirically determine the suitability of the TAGAP tagap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAGAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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