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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse brain tissue slide using MBS7604699 (TAC1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

Rabbit TAC1 Polyclonal Antibody | anti-TAC1 antibody

TAC1 Rabbit Polyclonal

Gene Names
TAC1; NK2; NPK; NKNA; TAC2; Hs.2563
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
TAC1; Polyclonal Antibody; TAC1 Rabbit Polyclonal; anti-TAC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
129
Applicable Applications for anti-TAC1 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
Tachykinin, precursor 1
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded mouse brain tissue slide using MBS7604699 (TAC1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded mouse brain tissue slide using MBS7604699 (TAC1 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer (pH9) .)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
11,376 Da
NCBI Official Full Name
TAC1
NCBI Official Synonym Full Names
tachykinin precursor 1
NCBI Official Symbol
TAC1
NCBI Official Synonym Symbols
NK2; NPK; NKNA; TAC2; Hs.2563
NCBI Protein Information
protachykinin-1
UniProt Protein Name
Protachykinin-1
Protein Family
UniProt Gene Name
TAC1
UniProt Synonym Gene Names
NKA; NKNA; TAC2; NKA; NPK
UniProt Entry Name
TKN1_HUMAN

NCBI Description

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Uniprot Description

TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: axon; cell soma; extracellular region; extracellular space; plasma membrane

Molecular Function: protein binding; receptor binding; substance P receptor binding

Biological Process: antibacterial humoral response; antifungal humoral response; associative learning; cell-cell signaling; defense response to Gram-negative bacterium; defense response to Gram-positive bacterium; detection of abiotic stimulus; elevation of cytosolic calcium ion concentration; inflammatory response; innate immune response; insemination; long-term memory; negative regulation of heart rate; neuropeptide signaling pathway; positive regulation of action potential; positive regulation of acute inflammatory response; positive regulation of lymphocyte proliferation; positive regulation of ossification; positive regulation of saliva secretion; positive regulation of stress fiber formation; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; regulation of blood pressure; response to hormone stimulus; response to lipopolysaccharide; response to morphine; response to pain; response to yeast; sensory perception of pain; synaptic transmission; tachykinin signaling pathway

Research Articles on TAC1

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Product Notes

The TAC1 tac1 (Catalog #AAA7604699) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TAC1 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TAC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the TAC1 tac1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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