Rabbit SYVN1 Polyclonal Antibody | anti-SYVN1 antibody

Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) SYVN1 Polyclonal Antibody

• Gene Names: syvn1; zgc:55735; zgc:77108; wu:fk91f10
• Reactivity: Danio rerio (Zebrafish)(Brachydanio rerio)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: SYVN1; Polyclonal Antibody; Rabbit anti-Danio rerio (Zebrafish)(Brachydanio rerio) SYVN1 Polyclonal Antibody; SYVN1 Antibody; E3 ubiquitin-protein ligase synoviolin; EC 2.3.2.27; RING-type E3 ubiquitin transferase synoviolin; Synovial apoptosis inhibitor 1; syvn1 hrd1 zgc:55735 zgc:77108; anti-SYVN1 antibody

• Host: Rabbit
• Reactivity: Danio rerio (Zebrafish)(Brachydanio rerio)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-SYVN1 antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Danio rerio (Zebrafish) (Brachydanio rerio) syvn1 protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 134035038
• NCBI GeneID: 335226
• UniProt Accession #: Q803I8; Q6NYA5
• Molecular Weight: 68,757 Da
• NCBI Official Full Name: E3 ubiquitin-protein ligase synoviolin
• NCBI Official Synonym Full Names: synovial apoptosis inhibitor 1, synoviolin
• NCBI Official Symbol: syvn1
• NCBI Official Synonym Symbols: zgc:55735; zgc:77108; wu:fk91f10
• NCBI Protein Information: E3 ubiquitin-protein ligase synoviolin
• UniProt Protein Name: E3 ubiquitin-protein ligase synoviolin
• Protein Family: E3 ubiquitin-protein ligase
• UniProt Gene Name: syvn1
• UniProt Synonym Gene Names: hrd1
• UniProt Entry Name: SYVN1_DANRE

Uniprot Description

Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins. Protects cells from ER stress-induced apoptosis. Sequesters p53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis ().