Rabbit anti-Human SYT2 Polyclonal Antibody | anti-SYT2 antibody
SYT2, ID (SYT2, Synaptotagmin-2, Synaptotagmin II) (MaxLight 650)
Gene Names
SYT2; SytII
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
SYT2; Polyclonal Antibody; ID (SYT2; Synaptotagmin-2; Synaptotagmin II) (MaxLight 650); Synaptotagmin II; anti-SYT2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight650.
Applicable Applications for anti-SYT2 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
SYT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-272 amino acids from the Central region of human SYT2.
Conjugate
MaxLight650
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight650 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Related Product Information for anti-SYT2 antibody
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).
Product Categories/Family for anti-SYT2 antibody
References
Young, S.M. Jr., et al. Neuron 63(4):482-496(2009). Han, C., et al. J. Immunol. 182(5):2986-2996(2009). Laohavisit, A., et al. Plant Cell 21(2):479-493(2009). Shi, J., et al. Biochem. Biophys. Res. Commun. 374(2):331-335(2008). Lee, B.H., et al. Mol. Cell 15(5):741-751(2004).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,872 Da
NCBI Official Full Name
synaptotagmin-2
NCBI Official Synonym Full Names
synaptotagmin II
NCBI Official Symbol
SYT2
NCBI Official Synonym Symbols
SytII
NCBI Protein Information
synaptotagmin-2; synaptotagmin 2
UniProt Protein Name
Synaptotagmin-2
Protein Family
UniProt Gene Name
SYT2
UniProt Synonym Gene Names
SytII
UniProt Entry Name
SYT2_HUMAN
Uniprot Description
SYT2: May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. Belongs to the synaptotagmin family.
Protein type: Lipid-binding; Membrane protein, integral; Calcium-binding; Vesicle
Chromosomal Location of Human Ortholog: 1q32.1
Cellular Component: synaptic vesicle membrane; intracellular membrane-bound organelle; plasma membrane; integral to membrane; cell junction
Molecular Function: protein binding; calcium-dependent phospholipid binding; transporter activity; calcium ion binding
Biological Process: transport; pathogenesis
Disease: Myasthenic Syndrome, Presynaptic, Congenital, With Or Without Motor Neuropathy
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Product Notes
The SYT2 syt2 (Catalog #AAA6353014) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SYT2, ID (SYT2, Synaptotagmin-2, Synaptotagmin II) (MaxLight 650) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SYT2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SYT2 syt2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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