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Goat Syntrophin gamma 1 Polyclonal Antibody | anti-SNTG1 antibody

Goat anti-Syntrophin gamma 1 Antibody

Gene Names
SNTG1; SYN4; G1SYN
Reactivity
Expected from sequence similarity: Human
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Syntrophin gamma 1; Polyclonal Antibody; Goat anti-Syntrophin gamma 1 Antibody; SNTG1; SYN4; G1SYN; syntrophin; gamma 1; gamma1-syntrophin; syntrophin 4 gamma1-syntrophin; syntrophin 4; SNTG1 antibody; SYN4 antibody; G1SYN antibody; gamma 1 antibody; gamma1-syntrophin antibody; syntrophin 4 gamma1-syntrophin antibody; syntrophin 4 antibody; anti-SNTG1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
ASSATTSKAKYTT
Sequence Length
517
Applicable Applications for anti-SNTG1 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Preliminary experiments gave no signal but low background in Human Testis and Brain extracts at up to 1ug/ml.
Immunogen
Peptide with sequence C-ASSATTSKAKYTT, from the C Terminus of the protein sequence according to NP_061840.1.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,684 Da
NCBI Official Full Name
gamma-1-syntrophin isoform 1
NCBI Official Synonym Full Names
syntrophin gamma 1
NCBI Official Symbol
SNTG1
NCBI Official Synonym Symbols
SYN4; G1SYN
NCBI Protein Information
gamma-1-syntrophin
UniProt Protein Name
Gamma-1-syntrophin
Protein Family
UniProt Gene Name
SNTG1
UniProt Synonym Gene Names
G1SYN; SYN4
UniProt Entry Name
SNTG1_HUMAN

NCBI Description

The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This family member plays a role in mediating gamma-enolase trafficking to the plasma membrane and in enhancing its neurotrophic activity. Mutations in this gene are associated with idiopathic scoliosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]

Uniprot Description

SNTG1: Adapter protein that binds to and probably organizes the subcellular localization of a variety of proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex. May participate in regulating the subcellular location of diacylglycerol kinase-zeta to ensure that diacylglycerol is rapidly inactivated following receptor activation. Belongs to the syntrophin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 8q11.21

Cellular Component: cytoplasm; cytoskeleton; nucleus; syntrophin complex

Molecular Function: actin binding; protein C-terminus binding; structural molecule activity

Biological Process: cell communication; positive regulation of defense response to virus by host

Research Articles on SNTG1

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Product Notes

The SNTG1 sntg1 (Catalog #AAA421349) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Syntrophin gamma 1 Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's Syntrophin gamma 1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Preliminary experiments gave no signal but low background in Human Testis and Brain extracts at up to 1ug/ml. Researchers should empirically determine the suitability of the SNTG1 sntg1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: ASSATTSKAK YTT. It is sometimes possible for the material contained within the vial of "Syntrophin gamma 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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