Goat Synphilin 1 Polyclonal Antibody | anti-SNCAIP antibody
Synphilin 1 antibody
Gene Names
SNCAIP; Sph1; SYPH1
Reactivity
To be determined by end-user
Applications
ELISA, Immunohistochemistry, Western Blot
Synonyms
Synphilin 1; Polyclonal Antibody; Synphilin 1 antibody; Polyclonal Synphilin 1; Anti-Synphilin 1; Synphilin-1; Synphilin -1; anti-SNCAIP antibody
Host
Goat
Reactivity
To be determined by end-user
Clonality
Polyclonal
Form/Format
Supplied as liquid whole serum without preservative
Sequence Length
603
Applicable Applications for anti-SNCAIP antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
ELISA: >1:10,655
WB: >1:2,000
WB: >1:2,000
Biological Significance
Synphilin-1 is a cytoplasmic protein that is enriched in the neurophil of normal human brain. Although the exact function of synphilin-1 is unknown, it may possibly have a role as a cytoskeletal protein based on the presence of ankyrin-like repeats and an ATP, GTP-binding domain. It has been shown to be novel is its ability to associate in vivo with a-synuclein to form cytoplasmic eosinophilic inclusions. Additionally, it has been observed to be present in Lewy bodies of Parkinson disease, which are composed of a-synuclein. Because synphilin-1 is not found in protein aggregates of Alzheimer?s disease, it appears to be specific for a-synuclein-containing lesions. Synphilin-1 may facilitate the aggregation of a-synuclein into Lewy bodies.
Immunogen
Synphilin 1 antibody was raised in goat using a peptide; SLELNGEKDKDKGRTLQRT, as the immunogen.
Preparation and Storage
Store at 4 degree C for short term storage. Aliquot and store at -20 degree C for long term storage. Avoid repeated freeze/thaw cycles.
Related Product Information for anti-SNCAIP antibody
Goat polyclonal Synphilin 1 antibody
Product Categories/Family for anti-SNCAIP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
6,888 Da
NCBI Official Full Name
synphilin-1 isoform 1A
NCBI Official Synonym Full Names
synuclein, alpha interacting protein
NCBI Official Symbol
SNCAIP
NCBI Official Synonym Symbols
Sph1; SYPH1
NCBI Protein Information
synphilin-1
UniProt Protein Name
Synphilin-1
Protein Family
UniProt Gene Name
SNCAIP
UniProt Entry Name
Q6L980_HUMAN
NCBI Description
This gene encodes a protein containing several protein-protein interaction domains, including ankyrin-like repeats, a coiled-coil domain, and an ATP/GTP-binding motif. The encoded protein interacts with alpha-synuclein in neuronal tissue and may play a role in the formation of cytoplasmic inclusions and neurodegeneration. A mutation in this gene has been associated with Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Research Articles on SNCAIP
Similar Products
Product Notes
The SNCAIP sncaip (Catalog #AAA535379) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Synphilin 1 antibody reacts with To be determined by end-user and may cross-react with other species as described in the data sheet. AAA Biotech's Synphilin 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). ELISA: >1:10,655 WB: >1:2,000. Researchers should empirically determine the suitability of the SNCAIP sncaip for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Synphilin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
