Rabbit SUSD2 Polyclonal Antibody | anti-SUSD2 antibody

Rabbit Polyclonal to Human SUSD2

Cat. Num. AAA247216

• Gene Names: SUSD2; BK65A6.2
• Reactivity: Gorilla, Human, Monkey; Predicted Reactivity: Chimpanzee, Orangutan (at least 90% immunogen sequence identity)
• Applications: Immunohistochemistry
• Purity: Immunoaffinity Purified
• Synonyms: SUSD2; Polyclonal Antibody; Rabbit Polyclonal to Human SUSD2; Anti-SUSD2 Antibody (Internal) IHC-plus; BK65A6.2; Sushi domain containing 2; Human SUSD2; anti-SUSD2 antibody

• Host: Rabbit
• Reactivity: Gorilla, Human, Monkey; Predicted Reactivity: Chimpanzee, Orangutan (at least 90% immunogen sequence identity)
• Clonality: Polyclonal
• Specificity: Human SUSD2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.1% sodium azide.
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 822

• Applicable Applications for anti-SUSD2 antibody: Immunohistochemistry (IHC - Paraffin)
• Application Notes: IHC-P (15 ug/ml); Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...
• Target Species: Human
• Immunogen Description: Synthetic 18 amino acid peptide from internal region of human SUSD2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Chimpanzee, Orangutan (94%); Gibbon, Panda (89%); Galago, Opossum (83%).
• Immunogen Type: Synthetic peptide
• Immunogen: SUSD2 antibody was raised against synthetic 18 amino acid peptide from internal region of human SUSD2. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Chimpanzee, Orangutan (94%); Gibbon, Panda (89%); Galago, Opossum (83%).
• Antigen Modification: Internal
• Preparation and Storage: Long term: -70 degree C; Short term: +4 degree C

Immunohistochemistry (IHC)

(Anti-SUSD2 antibody IHC of human skin, sebaceous gland. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

Immunohistochemistry (IHC)

(Anti-SUSD2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)

NCBI and Uniprot Product Information

• NCBI GI #: 10092665
• NCBI GeneID: 56241
• NCBI Accession #: NP_062547.1
• NCBI GenBank Nucleotide #: NM_019601.3
• UniProt Accession #: Q9UGT4; Q9H5Y6
• Molecular Weight: 90,208 Da
• NCBI Official Full Name: sushi domain-containing protein 2
• NCBI Official Synonym Full Names: sushi domain containing 2
• NCBI Official Symbol: SUSD2
• NCBI Official Synonym Symbols: BK65A6.2
• NCBI Protein Information: sushi domain-containing protein 2; Sushi domain (SCR repeat) containing
• UniProt Protein Name: Sushi domain-containing protein 2
• Protein Family: Sushi domain-containing protein
• UniProt Gene Name: SUSD2
• UniProt Entry Name: SUSD2_HUMAN

Uniprot Description

SUSD2: May play a role in breast tumorigenesis. {ECO:0000269|PubMed:23131994}. Interacts with LGALS1; leads to an increased amount of LGALS1 on the cell surface. {ECO:0000269|PubMed:23131994}

Protein type: Tumor suppressor; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q11-q12

Cellular Component: integral to membrane; plasma membrane

Molecular Function: protein binding; scavenger receptor activity; polysaccharide binding

Biological Process: receptor-mediated endocytosis; immune response