Rabbit anti-Mouse, Rat Surfactant protein D Polyclonal Antibody | anti-Sftpd antibody

Surfactant protein D Rabbit pAb

Cat. Num. AAA4757068

• Gene Names: Sftpd; SP-D; Sftp4; AI573415
• Reactivity: Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Purity: Affinity purified
• Synonyms: Surfactant protein D; Polyclonal Antibody; Surfactant protein D Rabbit pAb; Pulmonary surfactant-associated protein D; surfactant associated protein D; SP-D; Sfpd; Sftp4; AI573415; anti-Sftpd antibody

• Host: Rabbit
• Reactivity: Mouse, Rat
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: Supplied in 50nM Tris-Glycine(pH7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

• Applicable Applications for anti-Sftpd antibody: Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: WB: 1:1000; IHC: 1:500
• Immunogen: Recombinant protein of mouse Surfactant protein D
• Conjugation: Unconjugated
• Modification: Unmodified
• Preparation and Storage: Store at -20 degree C. Stable for 12 months from date of receipt.

Western Blot (WB)

(Western blot detection of Surfactant protein D in Rat lung cell lysates using Surfactant protein D Rabbit pAb(1:1000 diluted).Predicted band size:38kDa.Observed band size:43kDa.)

Related Product Information for anti-Sftpd antibody

Contributes to the lung's defense against inhaled microorganisms, organic antigens and toxins. Interacts with compounds such as bacterial lipopolysaccharides, oligosaccharides and fatty acids and modulates leukocyte action in immune response. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties.MiscellaneousPulmonary surfactant consists of 90% lipid and 10% protein. There are 4 surfactant-associated proteins: 2 collagenous, carbohydrate-binding glycoproteins (SP-A and SP-D) and 2 small hydrophobic proteins (SP-B and SP-C).

Product Categories/Family for anti-Sftpd antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 1709879
• NCBI GeneID: 20390
• UniProt Accession #: P50404
• Molecular Weight: 37,688 Da
• NCBI Official Full Name: Pulmonary surfactant-associated protein D
• NCBI Official Synonym Full Names: surfactant associated protein D
• NCBI Official Symbol: Sftpd
• NCBI Official Synonym Symbols: SP-D; Sftp4; AI573415
• NCBI Protein Information: pulmonary surfactant-associated protein D; PSP-D; lung surfactant protein D
• UniProt Protein Name: Pulmonary surfactant-associated protein D
• Protein Family: Pulmonary surfactant-associated protein
• UniProt Gene Name: Sftpd
• UniProt Synonym Gene Names: Sftp4; PSP-D; SP-D
• UniProt Entry Name: SFTPD_MOUSE

Uniprot Description

SFTPD: Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. Belongs to the SFTPD family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: multivesicular body; proteinaceous extracellular matrix; extracellular space; collagen; rough endoplasmic reticulum; cytoplasm; extracellular region; cytoplasmic vesicle

Molecular Function: monosaccharide binding; identical protein binding; lipopolysaccharide binding; carbohydrate binding

Biological Process: negative regulation of phagocytosis; negative regulation of T cell proliferation; immune system process; positive regulation of phagocytosis; innate immune response; opsonization; respiratory gaseous exchange; regulation of liquid surface tension; surfactant homeostasis; alveolus development; negative regulation of interleukin-2 production