Rabbit anti-Human, Mouse SULT4A1 Polyclonal Antibody | anti-SULT4A1 antibody

SULT4A1, NT (Sulfotransferase 4A1, ST4A1, Brain Sulfotransferase-like Protein, hBR-STL, hBR-STL-1, Nervous System Sulfotransferase, NST, SULT4A1, SULTX3) (FITC)

Cat. Num. AAA6501512

• Gene Names: SULT4A1; NST; BRSTL1; SULTX3; BR-STL-1; DJ388M5.3; hBR-STL-1
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein G Affinity Chromatography.
• Synonyms: SULT4A1; Polyclonal Antibody; NT (Sulfotransferase 4A1; ST4A1; Brain Sulfotransferase-like Protein; hBR-STL; hBR-STL-1; Nervous System Sulfotransferase; NST; SULTX3) (FITC); anti-SULT4A1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SULT4A1. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein G Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
• Sequence Length: 284

• Applicable Applications for anti-SULT4A1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-1:500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from the N-term of human SULT4A1 (region common to both isoforms a and b) (KLH).
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western blot analysis of anti-SULT4A1a/b Pab in mouse cerebellum cell line lysate (35ug/lane). SULT4A1a/b(arrow) was detected using the purified Pab.)

Product Categories/Family for anti-SULT4A1 antibody

Antibodies; Enzymes; Sulfotransferase

References

1. Liyou, N.E., et al., J. Histochem. Cytochem. 51(12):1655-1664 (2003). 2. Weinshilboum, R.M., et al., FASEB J. 11(1):3-14 (1997). 3. Glatt, H., et al., Mutat. Res. 482(1-2), 27-40 (2001). 4. Sakakibara, Y., et al., Gene 285(1-2), 39-47 (2002). 5. Glatt, H., et al., Toxicol. Lett. 112-113, 341-348 (2000).

NCBI and Uniprot Product Information

• NCBI GI #: 7657633
• NCBI GeneID: 25830
• NCBI Accession #: NP_055166; NP_795343
• NCBI GenBank Nucleotide #: NP_055166.1
• UniProt Accession #: Q9BR01
• Molecular Weight: 33.084
• NCBI Official Full Name: sulfotransferase 4A1
• NCBI Official Synonym Full Names: sulfotransferase family 4A member 1
• NCBI Official Symbol: SULT4A1
• NCBI Official Synonym Symbols: NST; BRSTL1; SULTX3; BR-STL-1; DJ388M5.3; hBR-STL-1
• NCBI Protein Information: sulfotransferase 4A1
• UniProt Protein Name: Sulfotransferase 4A1
• Protein Family: Sulfotransferase
• UniProt Gene Name: SULT4A1
• UniProt Synonym Gene Names: SULTX3
• UniProt Entry Name: ST4A1_HUMAN

NCBI Description

This gene encodes a member of the sulfotransferase family. The encoded protein is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. Polymorphisms in this gene may be associated with susceptibility to schizophrenia. [provided by RefSeq, Jul 2008]

Uniprot Description

SULT4A1: Atypical sulfotransferase family member with very low affinity for 3'-phospho-5'-adenylyl sulfate (PAPS) and very low catalytic activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphthylamine, and 2-beta-naphthol. May have a role in the metabolism of drugs and neurotransmitters in the CNS. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.8.2.-; Transferase

Chromosomal Location of Human Ortholog: 22q13.2

Cellular Component: cytosol

Molecular Function: sulfotransferase activity; protein binding

Biological Process: steroid metabolic process; xenobiotic metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process