Rabbit anti-Human, Mouse SULT1C1 Polyclonal Antibody | anti-SULT1C1 antibody

SULT1C1, ID (Sulfotransferase 1C2, ST1C2, Sulfotransferase 1C1, SULT1C#1, humSULTC2, SULT1C2) (FITC)

Cat. Num. AAA6501479

• Gene Names: SULT1C2; ST1C1; ST1C2; SULT1C1; humSULTC2
• Reactivity: Human, Mouse
• Applications: Western Blot
• Purity: Purified by Protein G Affinity Chromatography.
• Synonyms: SULT1C1; Polyclonal Antibody; ID (Sulfotransferase 1C2; ST1C2; Sulfotransferase 1C1; SULT1C#1; humSULTC2; SULT1C2) (FITC); anti-SULT1C1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SULT1C1. Species Crossreactivity: mouse.
• Purity/Purification: Purified by Protein G Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-SULT1C1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-1:500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide selected from within the central region of human SULT1C1 (KLH).
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(The anti-SULT1C1 Pab is used in Western blot to detect SULT1C1 in mouse kidney tissue lysate.)

Product Categories/Family for anti-SULT1C1 antibody

Antibodies; Enzymes; Sulfotransferase

NCBI and Uniprot Product Information

• NCBI GI #: 29029530
• NCBI GeneID: 6819
• NCBI Accession #: NP_789795
• NCBI GenBank Nucleotide #: NM_176825.2
• UniProt Accession #: O00338; Q53SG4; B2R813
• Molecular Weight: 35,868 Da
• NCBI Official Full Name: sulfotransferase 1C2 isoform b
• NCBI Official Synonym Full Names: sulfotransferase family 1C member 2
• NCBI Official Symbol: SULT1C2
• NCBI Official Synonym Symbols: ST1C1; ST1C2; SULT1C1; humSULTC2
• NCBI Protein Information: sulfotransferase 1C2
• UniProt Protein Name: Sulfotransferase 1C2
• Protein Family: Sulfotransferase
• UniProt Gene Name: SULT1C2
• UniProt Synonym Gene Names: SULT1C1; ST1C2; SULT1C#1
• UniProt Entry Name: ST1C2_HUMAN

NCBI Description

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

SULT1C1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of drugs, xenobiotic compounds, hormones, and neurotransmitters. May be involved in the activation of carcinogenic hyroxylamines. Shows activity towards p-nitrophenol and N-hydroxy-2-acetylamino-fluorene (N-OH-2AAF). Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.8.2.-

Chromosomal Location of Human Ortholog: 2q12.3

Cellular Component: cytoplasm; cytosol

Molecular Function: sulfotransferase activity

Biological Process: xenobiotic metabolic process; sulfation; amine metabolic process; 3'-phosphoadenosine 5'-phosphosulfate metabolic process