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Western Blot (WB) (SUDS3 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).)

Rabbit SUDS3 Polyclonal Antibody | anti-SUDS3 antibody

SUDS3 Antibody (N-term)

Gene Names
SUDS3; SDS3; SAP45
Reactivity
Human, mouse (Predicted Reactivity: Bovine)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SUDS3; Polyclonal Antibody; SUDS3 Antibody (N-term); Sin3 histone deacetylase corepressor complex component SDS3; 45 kDa Sin3-associated polypeptide; Suppressor of defective silencing 3 protein homolog; SAP45; SDS3; anti-SUDS3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SUDS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-98 amino acids from the N-terminal region of human SUDS3.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.35 (varies by lot)
Sequence Positions
72-98
Sequence Length
328
Applicable Applications for anti-SUDS3 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(SUDS3 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).)

Western Blot (WB) (SUDS3 Antibody (N-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).)

Western Blot (WB)

(SUDS3 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).)

Western Blot (WB) (SUDS3 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the SUDS3 antibody detected the SUDS3 protein (arrow).)
Related Product Information for anti-SUDS3 antibody
SDS3 is a subunit of the histone deacetylase (see HDAC1;
MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex
(Fleischer et al., 2003 [PubMed 12724404]).
References
Silveira, A.C., et al. Cancer Lett. 276(1):32-37(2009)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Hurst, D.R., et al. Biochem. Biophys. Res. Commun. 348(4):1429-1435(2006)
Fleischer, T.C., et al. Mol. Cell. Biol. 23(10):3456-3467(2003)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38136
NCBI Official Full Name
sin3 histone deacetylase corepressor complex component SDS3
NCBI Official Synonym Full Names
suppressor of defective silencing 3 homolog (S. cerevisiae)
NCBI Official Symbol
SUDS3
NCBI Official Synonym Symbols
SDS3; SAP45
NCBI Protein Information
sin3 histone deacetylase corepressor complex component SDS3
UniProt Protein Name
Sin3 histone deacetylase corepressor complex component SDS3
UniProt Gene Name
SUDS3
UniProt Synonym Gene Names
SAP45; SDS3
UniProt Entry Name
SDS3_HUMAN

NCBI Description

SDS3 is a subunit of the histone deacetylase (see HDAC1; MIM 601241)-dependent SIN3A (MIM 607776) corepressor complex (Fleischer et al., 2003 [PubMed 12724404]).[supplied by OMIM, Mar 2008]

Uniprot Description

SDS3: component of the Sin3/histone deacetylase corepressor complex. Essential for pericentric heterochromatin formation and chromosome segregation in mammalian cells.

Protein type: Helicase

Chromosomal Location of Human Ortholog: 12q24.23

Cellular Component: nucleoplasm; Sin3 complex; cytoplasm; nucleus

Molecular Function: protein binding; enzyme binding; protein homodimerization activity; histone deacetylase binding; histone deacetylase activity

Biological Process: establishment and/or maintenance of chromatin architecture; substantia nigra development; transcription, DNA-dependent; apoptosis; positive regulation of apoptosis; negative regulation of gene expression, epigenetic; gene expression; histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; regulation of gene expression, epigenetic

Research Articles on SUDS3

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Product Notes

The SUDS3 suds3 (Catalog #AAA9205808) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 72-98. The SUDS3 Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's SUDS3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the SUDS3 suds3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUDS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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