Rabbit STXBP5 Polyclonal Antibody | anti-STXBP5 antibody
STXBP5 Antibody
Gene Names
STXBP5; LGL3; LLGL3; Nbla04300
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
STXBP5; Polyclonal Antibody; STXBP5 Antibody; FLJ30922; Lethal(2) giant larvae protein homolog 3; LGL3; LLGL3; MGC141942; MGC141968; Nbla04300; Syntaxin binding protein 5; Tomosyn 1; anti-STXBP5 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
STXBP5 Antibody detects endogenous levels of STXBP5.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-STXBP5 antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human STXBP5.
Conjugation
Unconjugated
Similarity
Belongs to the WD repeat L(2)GL family.
Subunit Structure
Interacts with STX1A and STX1B via its v-SNARE homology domain. Part of a complex that contains STX1, STXBP5, SNAP25 and SYT1. Part of a complex that contains STXBP5, STX4A and SNAP23 (By similarity).
Function
Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity).
Note
Cytoplasmic, and associated with vesicular membranes and the plasma membrane. Detected at synapses and on synaptic vesicles (By similarity).
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Product Categories/Family for anti-STXBP5 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
121,597 Da
NCBI Official Full Name
syntaxin-binding protein 5 isoform b
NCBI Official Synonym Full Names
syntaxin binding protein 5 (tomosyn)
NCBI Official Symbol
STXBP5
NCBI Official Synonym Symbols
LGL3; LLGL3; Nbla04300
NCBI Protein Information
syntaxin-binding protein 5; lethal(2) giant larvae protein homolog 3; putative protein product of Nbla04300; tomosyn; tomosyn-1
UniProt Protein Name
Syntaxin-binding protein 5
Protein Family
UniProt Gene Name
STXBP5
UniProt Synonym Gene Names
LLGL3
UniProt Entry Name
STXB5_HUMAN
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Product Notes
The STXBP5 stxbp5 (Catalog #AAA9630196) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STXBP5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's STXBP5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the STXBP5 stxbp5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STXBP5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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