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Western Blot (WB) (Western Blot analysis in MDA-MB231 cell line lysates (35ug/lane) using MBS647072. This demonstrates MBS647072 detected the STX4 protein (arrow).)

Rabbit anti-Human STX4 Polyclonal Antibody | anti-STX4 antibody

STX4, ID (STX4, STX4A, Syntaxin-4, Renal carcinoma antigen NY-REN-31)

Gene Names
STX4; STX4A; p35-2
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
STX4; Polyclonal Antibody; ID (STX4; STX4A; Syntaxin-4; Renal carcinoma antigen NY-REN-31); Anti -STX4; anti-STX4 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Human
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Applicable Applications for anti-STX4 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Immunogen
STX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 131-160 amino acids selected from the Central region of human STX4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis in MDA-MB231 cell line lysates (35ug/lane) using MBS647072. This demonstrates MBS647072 detected the STX4 protein (arrow).)

Western Blot (WB) (Western Blot analysis in MDA-MB231 cell line lysates (35ug/lane) using MBS647072. This demonstrates MBS647072 detected the STX4 protein (arrow).)
Related Product Information for anti-STX4 antibody
Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes (By similarity). May also play a role in docking of synaptic vesicles at presynaptic active zones.
Product Categories/Family for anti-STX4 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,180 Da
NCBI Official Full Name
syntaxin-4 isoform 2
NCBI Official Synonym Full Names
syntaxin 4
NCBI Official Symbol
STX4
NCBI Official Synonym Symbols
STX4A; p35-2
NCBI Protein Information
syntaxin-4; syntaxin 4A (placental); renal carcinoma antigen NY-REN-31
UniProt Protein Name
Syntaxin-4
UniProt Gene Name
STX4
UniProt Synonym Gene Names
STX4A
UniProt Entry Name
STX4_HUMAN

Uniprot Description

Function: Plasma membrane t-SNARE that mediates docking of transport vesicles. Necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes

By similarity. May also play a role in docking of synaptic vesicles at presynaptic active zones.

Subunit structure: Component of the SNARE complex composed of STX4, SNAP23 and VAMP7 that interacts with SYT7 during lysosomal exocytosis. Found in a complex with VAMP8 and SNAP23. Detected in a complex with SNAP23 and STXBP4. Interacts with VAMP2. Interacts with SNAP23 and SNAPIN. Interacts with LLGL1. Interacts (via C-terminus) with CENPF. Interacts with DOC2B. Interacts with STXBP6. Interacts with STXBP3; excludes interaction with DOC2B and SNAP25. Interacts with STXBP4; excludes interaction with VAMP2

By similarity.

Subcellular location: Cell membrane; Single-pass type IV membrane protein

Potential.

Tissue specificity: Expressed in neutrophils and neutrophil-differentiated HL-60 cells. Expression in neutrophils increases with differentiation. Ref.3

Sequence similarities: Belongs to the syntaxin family.Contains 1 t-SNARE coiled-coil homology domain.

Research Articles on STX4

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Product Notes

The STX4 stx4 (Catalog #AAA647072) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STX4, ID (STX4, STX4A, Syntaxin-4, Renal carcinoma antigen NY-REN-31) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STX4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in Western Blot, ELISA Dilution: ELISA: 1:1,000 Western Blot: 1:100-500. Researchers should empirically determine the suitability of the STX4 stx4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STX4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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