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Western Blot (WB) (Western blotAll lanes: STOX1 antibody at 8ug/ml+HepG-2 whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 111,26,20 kDaObserved band size: 111 kDa)

Rabbit anti-Human STOX1 Polyclonal Antibody | anti-STOX1 antibody

STOX1 Antibody

Gene Names
STOX1; PEE4; C10orf24
Reactivity
Human
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>95%, Protein G purified
Synonyms
STOX1; Polyclonal Antibody; STOX1 Antibody; Storkhead-box protein 1; Winged-helix domain-containing protein; C10orf24; anti-STOX1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Sequence Length
227
Applicable Applications for anti-STOX1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB:1:1000-1:5000, IHC:1:20-1:200
Immunogen
Recombinant Human Storkhead-box protein 1 protein (559-858AA)
Conjugation
Non-conjugated
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-133266 / sc-133268
Species
Homo sapiens (Human)
Research Area
Epigenetics and Nuclear Signaling
Target Names
STOX1
Preparation and Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: STOX1 antibody at 8ug/ml+HepG-2 whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 111,26,20 kDaObserved band size: 111 kDa)

Western Blot (WB) (Western blotAll lanes: STOX1 antibody at 8ug/ml+HepG-2 whole cell lysateGoat polyclonal to rabbit at 1/10000 dilutionPredicted band size: 111,26,20 kDaObserved band size: 111 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human brain tissue using MBS7004465 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human brain tissue using MBS7004465 at dilution of 1:100)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human skin tissue using MBS7004465 at dilution of 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human skin tissue using MBS7004465 at dilution of 1:100)
Related Product Information for anti-STOX1 antibody
Involved in regulating the levels of reactive oxidative species and reactive nitrogen species and in mitochondrial homeostasis in the placenta (PubMed:24738702). Required for regulation of inner ear epithelial cell proliferation via the AKT signaling pathway.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
storkhead-box protein 1 isoform b
NCBI Official Synonym Full Names
storkhead box 1
NCBI Official Symbol
STOX1
NCBI Official Synonym Symbols
PEE4; C10orf24
NCBI Protein Information
storkhead-box protein 1
UniProt Protein Name
Storkhead-box protein 1
Protein Family
UniProt Gene Name
STOX1
UniProt Synonym Gene Names
C10orf24
UniProt Entry Name
STOX1_HUMAN

NCBI Description

The protein encoded by this gene may function as a DNA binding protein. Mutations in this gene are associated with pre-eclampsia/eclampsia 4 (PEE4). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

Uniprot Description

STOX1: Defects in STOX1 are the cause of pre-eclampsia/eclampsia 4 (PEE4); also known as gestational proteinuric hypertension. Preeclampsia is a pregnancy-associated disease with maternal symptoms but placental origin. Unlike most other human disorders, it impacts 2 individuals, the mother and her child, both of whom can be severely affected. The pathological mechanism of PEE4 involves the loss of function of STOX1 in the placenta. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: cell cortex; centrosome; cytoplasm; nucleolus; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: cell division; inner ear development; mitosis; positive regulation of cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of peptidyl-serine phosphorylation; positive regulation of protein kinase B signaling cascade; regulation of gene expression; regulation of mitochondrial membrane potential; transcription, DNA-dependent

Disease: Preeclampsia/eclampsia 4

Research Articles on STOX1

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Product Notes

The STOX1 stox1 (Catalog #AAA7004465) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STOX1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STOX1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). WB:1:1000-1:5000, IHC:1:20-1:200. Researchers should empirically determine the suitability of the STOX1 stox1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STOX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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