Rabbit anti-Human STOML2 Polyclonal Antibody | anti-STOML2 antibody

STOML2 Polyclonal Antibody

Cat. Num. AAA2554043

• Gene Names: STOML2; SLP-2; HSPC108
• Reactivity: Human
• Applications: Immunohistochemistry
• Purity: Affinity Purification
• Synonyms: STOML2; Polyclonal Antibody; STOML2 Polyclonal Antibody; EPB72 like protein 2; HSPC108; OTTHUMP00000021320; Paraprotein target 7; SLP 2; STML2_HUMAN; Stomatin (EPB72) like 2; Stomatin like 2; Stomatin like protein 2; mitochondrial; anti-STOML2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.05% Proclin300, 50% glycerol, pH7.3.
• Concentration: 2 mg/mL (varies by lot)
• Sequence Length: 311

• Applicable Applications for anti-STOML2 antibody: Immunohistochemistry (IHC)
• Application Notes: IHC: 1:100-1:400
• Immunogen: Recombinant Human Stomatin-like protein 2, mitochondrial protien
• Conjugation: Unconjugated
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer using STOML2 Polyclonal Antibody at dilution of 1:200)

Related Product Information for anti-STOML2 antibody

Human stomatin (band 7.2b) is a 31-kDa erythrocyte membrane protein of unknown function but implicated in the control of ion channel permeability, mechanoreception, and lipid domain organization. Stomatin (EPB72)-like 2 (STOML2, synonyms: SLP-2, HSPC108) is a 38.5-kDa protein that is overall approximately 20% similar to human stomatin. STOML2 is also present in mature human erythrocytes, but lacks a characteristic NH(2)-terminal hydrophobic domain found in other stomatin homologues. STOML2 may link stomatin or other integral membrane proteins to the peripheral cytoskeleton and thereby play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.

Product Categories/Family for anti-STOML2 antibody

Cancer

NCBI and Uniprot Product Information

• NCBI GI #: 559098406
• NCBI GeneID: 30968
• NCBI Accession #: NP_001273960.1
• NCBI GenBank Nucleotide #: NM_001287031.1
• UniProt Accession #: Q9UJZ1; O60376; Q53G29; Q96FY2; Q9P042; B4E1K7; D3DRN3
• Molecular Weight: 33,337 Da
• NCBI Official Full Name: stomatin-like protein 2, mitochondrial isoform b
• NCBI Official Synonym Full Names: stomatin like 2
• NCBI Official Symbol: STOML2
• NCBI Official Synonym Symbols: SLP-2; HSPC108
• NCBI Protein Information: stomatin-like protein 2, mitochondrial
• UniProt Protein Name: Stomatin-like protein 2, mitochondrial
• Protein Family: Stomatin-like protein
• UniProt Gene Name: STOML2
• UniProt Synonym Gene Names: SLP2; SLP-2; Paratarg-7

Uniprot Description

Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.