Immunohistochemistry (IHC)
(Immunochemical staining of human STK16 in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Rabbit anti-Human STK16 Polyclonal Antibody | anti-STK16 antibody
Anti-STK16 Antibody, Rabbit Polyclonal
Gene Names
STK16; PSK; KRCT; MPSK; TSF1; hPSK; PKL12
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
STK16; Polyclonal Antibody; Anti-STK16 Antibody; Rabbit Polyclonal; STK16/PKL12 Antibody; Rabbit PAb; Antigen Affinity Purified; serine/threonine kinase 16; Anti-KRCT Antibody; Anti-MPSK Antibody; Anti-PKL12 Antibody; Anti-TSF1 Antibody; anti-STK16 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human STK16/PKL12
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-STK16 antibody
Immunohistochemistry-Paraffin (IHC-P)
Application Notes
IHC-P: 1:500-1:2000
Immunogen
Recombinant Human STK16/PKL12 Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human STK16/PKL12 (rh STK16/PKL12). STK16/PKL12 specific IgG was purified by Human STK16/PKL12 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human STK16 in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Immunohistochemistry (IHC)
(Immunochemical staining of human STK16 in human breast carcinoma with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-STK16 antibody
Serine/threonine-protein kinase 16, also known as myristoylated and palmitoylated serine/threonine-protein kinase, Protein kinase PKL12, TGF-beta-stimulated factor 1, TSF-1, MPSK1 and STK16, is a membrane protein that is ubiquitously expressed at very low levels. STK16/MPSK1 belongs to the protein kinase superfamily and Ser/Thr protein kinase family. It contains one protein kinase domain. Transforming growth factor-beta (TGF-beta) shows a variety of biological activities in various organs or cells. Some factors such as Smads (Sma and Mad proteins) and TGF-beta activating kinase 1 have been characterized as signalling molecules downstream of TGF-beta. Several TGF-beta response elements have been identified such as cAMP response element, Smad binding element, and recognition sites for activating protein-1 and stimulating protein-1 in various gene promoters. STK16/MPSK1 is a unique factor with two biological functions, transcriptional regulation and protein phosphorylation, that may be involved in TGF-beta signals. STK16/MPSK1 is a protein kinase that acts on both serine and threonine residues. STK16/MPSK1 possessed DNA-binding ability and activated the TGF-beta responsive CNP promoter or vascular endothelial growth factor gene promoter which possesses a sequence element analogous to the TGF-beta responsive GC-rich element of the CNP promoter. STK16/MPSK1 did not directly activate a Smads-dependent promoter from plasminogen activator inhibitor 1 gene, but it showed enhancement in co-operation with Smad3 and Smad4. STK16/MPSK1 mRNA as well as its protein level were stimulated by TGF-beta treatment.
References
Ligos J.M., et al., 1998, Biochem. Biophys. Res.Commun. 249:380-4. Berson A.E., et al., 1999, Biochem. Biophys. Res. Commun. 259:533-8. Ohta S., et al., 2000, Biochem. J. 350:395-404. Guinea, B. et al., 2006, Exp Cell Res. 312 (2):135-44.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
34,656 Da
NCBI Official Full Name
Serine/threonine kinase 16
NCBI Official Synonym Full Names
serine/threonine kinase 16
NCBI Official Symbol
STK16
NCBI Official Synonym Symbols
PSK; KRCT; MPSK; TSF1; hPSK; PKL12
NCBI Protein Information
serine/threonine-protein kinase 16
Protein Family
Research Articles on STK16
Similar Products
Product Notes
The STK16 (Catalog #AAA8106272) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-STK16 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STK16 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry-Paraffin (IHC-P). IHC-P: 1:500-1:2000. Researchers should empirically determine the suitability of the STK16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STK16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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