Testing Data
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Rabbit STAT5a Polyclonal Antibody | anti-STAT5a antibody
STAT5a antibody
Gene Names
STAT5A; STATA5; STAT5A/MGF
Applications
Western Blot
Purity
Purified by Protein A affinity chromatography
Synonyms
STAT5a; Polyclonal Antibody; STAT5a antibody; Rabbit polyclonal STAT5a antibody; Polyclonal STAT5a antibody; Anti-STAT5a antibody; STAT5A antibody; signal transducer and activator of transcription 5A antibody; BOS_19069 antibody; mammary gland factor antibody; mammary gland factor STAT5A antibody; MGF antibody; RP23-279L23.4 antibody; signal transducer and activator of transcription 5 antibody; STAT5 antibody; Mammary Gland Factor antibody; STAT5A/MGF antibody; STATA5 antibody; anti-STAT5a antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A affinity chromatography
Form/Format
Liquid form in HEPES buffer with 0.15M NaCl,0.01% BSA,0.03% sodium azide, and 50% glycerol
Sequence Length
86
Applicable Applications for anti-STAT5a antibody
Western Blot (WB)
Application Notes
WB: 1:20000
Immunogen
STAT5a antibody was raised in Rabbit using a synthetic target peptide as the immunogen
Cross-Reactivity
Human, Mouse, Rat
Preparation and Storage
Aliquot and store for 1 year at-20 degree C.
Avoid freeze/thaw cycles.
Avoid freeze/thaw cycles.
Testing Data
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Testing Data
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Related Product Information for anti-STAT5a antibody
Signal transducer and activator of transcription (STAT), named after their dual role, generally mediate cytokine, growth factor and hormone receptor signal transduction. In mammals, seven STAT proteins have been identified. STAT5 has been implicated in cellular functions of proliferation, differentiation and apoptosis with relevance to processes of hematopoiesis and immunoregulation, reproduction, and lipid metabolism. Two highly homologous STAT5 isoforms, 96 kDa STAT5a and 94 kDa STAT5b, are encoded by two tandemly linked genes. Although both STAT5 isoforms are roughly 95% homologous at the level of cDNA, they exhibit both redundant and non-redundant functions in vivo, probably due to differences in their transactivation domain. Aberrant regulation of STAT5 has been observed in solid tumors as well as in patients with either chronic or acute myeloid leukemia. Kinase inhibitors are currently being developed to negatively regulate STAT5 activity for clinical purposes.
Product Categories/Family for anti-STAT5a antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
90,700 Da
NCBI Official Full Name
Stat5a, partial
NCBI Official Synonym Full Names
signal transducer and activator of transcription 5A
NCBI Official Symbol
STAT5A
NCBI Official Synonym Symbols
STATA5; STAT5A/MGF
NCBI Protein Information
signal transducer and activator of transcription 5A
UniProt Protein Name
Signal transducer and activator of transcription 5A
Protein Family
UniProt Gene Name
STAT5A
UniProt Synonym Gene Names
MGF
Uniprot Description
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation ().
Research Articles on STAT5a
Similar Products
Product Notes
The STAT5a stat5a (Catalog #AAA5310085) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's STAT5a can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:20000. Researchers should empirically determine the suitability of the STAT5a stat5a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAT5a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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