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Testing Data (HeLa cell lysate and FN alpha/gamma treated HeLa cell lysate probed with MBS627744 (1:100). Proteins were visualized using an IgG (HRP) goat anti-rabbit secondary and a chemiluminescence detection system.)

Rabbit anti-Human STAT 2 Polyclonal Antibody | anti-STAT2 antibody

STAT 2, Phosphorylated (Tyr689) (Signal Transducer and Activator of Transcription 2) (HRP)

Gene Names
Stat2; AW496480; 1600010G07Rik
Reactivity
Human
Applications
Western Blot, Immunoprecipitation
Purity
Purified by affinity chromatography
Synonyms
STAT 2; Polyclonal Antibody; Phosphorylated (Tyr689) (Signal Transducer and Activator of Transcription 2) (HRP); anti-STAT2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes STAT2 phosphorylated at Tyr689, Mr113kD. An uncharacterized band may appear at ~260kD in some lysates. Species Crossreactivity: human
Purity/Purification
Purified by affinity chromatography
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish Peroxidase (HRP).
Applicable Applications for anti-STAT2 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
KLH-conjugated synthetic peptide corresponding to mouse STAT2 phosphorylated at Tyr689 (NP_064347). Species sequence homology: mouse; 100%, rat; 89%
Conjugate
HRP
Antigen Modification
Phosphorylated
Note
Preservative Free
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.

Testing Data

(HeLa cell lysate and FN alpha/gamma treated HeLa cell lysate probed with MBS627744 (1:100). Proteins were visualized using an IgG (HRP) goat anti-rabbit secondary and a chemiluminescence detection system.)

Testing Data (HeLa cell lysate and FN alpha/gamma treated HeLa cell lysate probed with MBS627744 (1:100). Proteins were visualized using an IgG (HRP) goat anti-rabbit secondary and a chemiluminescence detection system.)

Immunoprecipitation (IP)

(IFN alpha treated HeLa cell lysate immunoprecipitated withMBS627744.)

Immunoprecipitation (IP) (IFN alpha treated HeLa cell lysate immunoprecipitated withMBS627744.)

Testing Data

(HeLa cell lysate (Lane 1) and IFN alpha/gamma treated HeLa cell lysate (Lane 2) were probed with MBS627744 (1:100). Proteins were visualized using an IgG (HRP) donkey anti-rabbit secondary and a chemiluminescence detection system.)

Testing Data (HeLa cell lysate (Lane 1) and IFN alpha/gamma treated HeLa cell lysate (Lane 2) were probed with MBS627744 (1:100). Proteins were visualized using an IgG (HRP) donkey anti-rabbit secondary and a chemiluminescence detection system.)
Product Categories/Family for anti-STAT2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
105,417 Da
NCBI Official Full Name
signal transducer and activator of transcription 2
NCBI Official Synonym Full Names
signal transducer and activator of transcription 2
NCBI Official Symbol
Stat2
NCBI Official Synonym Symbols
AW496480; 1600010G07Rik
NCBI Protein Information
signal transducer and activator of transcription 2
UniProt Protein Name
Signal transducer and activator of transcription 2
UniProt Gene Name
STAT2
UniProt Entry Name
STAT2_HUMAN

Uniprot Description

STAT2: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Binds to the IFN-stimulated response element (ISRE) and to the Gas element. This multiprotein transcription factor is termed ISGF3. Two alternatively spliced isoforms have been described.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 12q13.3

Cellular Component: nucleoplasm; cytoplasm; plasma membrane; cytosol

Molecular Function: identical protein binding; signal transducer activity; protein binding; DNA binding; transcription factor activity

Biological Process: regulation of transcription from RNA polymerase II promoter; viral reproduction; transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; JAK-STAT cascade; defense response to virus

Research Articles on STAT2

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Product Notes

The STAT2 stat2 (Catalog #AAA6500928) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STAT 2, Phosphorylated (Tyr689) (Signal Transducer and Activator of Transcription 2) (HRP) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's STAT 2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the STAT2 stat2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STAT 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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