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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS7604510 (ST8SIA3 antibody) at dilution of 1:50)

Rabbit ST8SIA3 Polyclonal Antibody | anti-ST8SIA3 antibody

ST8SIA3 Rabbit Polyclonal

Gene Names
ST8SIA3; SIAT8C; ST8SiaIII
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Synonyms
ST8SIA3; Polyclonal Antibody; ST8SIA3 Rabbit Polyclonal; anti-ST8SIA3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>=95% as determined by SDS-PAGE
Immunogen Affinity Purified
Form/Format
Liquid
Sequence Length
380
Applicable Applications for anti-ST8SIA3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen
ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sialyltransferase 3
Preparation and Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human liver using MBS7604510 (ST8SIA3 antibody) at dilution of 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human liver using MBS7604510 (ST8SIA3 antibody) at dilution of 1:50)

Western Blot (WB)

(mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7604510 (ST8SIA3 antibody) at dilution of 1:800)

Western Blot (WB) (mouse liver tissue were subjected to SDS PAGE followed by western blot with MBS7604510 (ST8SIA3 antibody) at dilution of 1:800)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
43,970 Da
NCBI Official Full Name
sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
NCBI Official Synonym Full Names
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
NCBI Official Symbol
ST8SIA3
NCBI Official Synonym Symbols
SIAT8C; ST8SiaIII
NCBI Protein Information
sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
UniProt Protein Name
Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase
UniProt Gene Name
ST8SIA3
UniProt Synonym Gene Names
SIAT8C; ST8SiaIII
UniProt Entry Name
SIA8C_HUMAN

NCBI Description

ST8SIA3 belongs to a family of sialyltransferases that form sialyl-alpha-2,8-sialyl-R linkages at the nonreducing termini of glycoconjugates (Lee et al., 1998 [PubMed 9826427]).[supplied by OMIM, Mar 2008]

Uniprot Description

ST8SIA3: May transfer sialic acid through alpha-2,8-linkages to alpha-2,3-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid. Belongs to the glycosyltransferase 29 family.

Protein type: Membrane protein, integral; EC 2.4.99.-; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series; Transferase

Chromosomal Location of Human Ortholog: 18q21.31

Cellular Component: Golgi membrane; integral to Golgi membrane

Molecular Function: alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity; sialic acid binding; sialyltransferase activity

Biological Process: ganglioside biosynthetic process; glycoprotein metabolic process; glycosphingolipid biosynthetic process; N-glycan processing; oligosaccharide metabolic process; protein amino acid glycosylation

Research Articles on ST8SIA3

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Product Notes

The ST8SIA3 st8sia3 (Catalog #AAA7604510) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ST8SIA3 Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ST8SIA3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the ST8SIA3 st8sia3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST8SIA3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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