Rabbit ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 Polyclonal Antibody | anti-ST3GAL6 antibody
Rabbit anti-human ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 polyclonal Antibody
WB : 1:500-1:5000 (Recommender dilution)
Positive WB detected in: Human placenta tissue, human heart tissue
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the sialyltransferase family. Members of this family are enzymes that transfer sialic acid from the activated cytidine 5'-monophospho-N-acetylneuraminic acid to terminal positions on sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins. This protein has high specificity for neolactotetraosylceramide and neolactohexaosylceramide as glycolipid substrates and may contribute to the formation of selectin ligands and sialyl Lewis X, a carbohydrate important for cell-to-cell recognition and a blood group antigen. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Sep 2012]
Uniprot Description
ST3GAL6: Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1. Belongs to the glycosyltransferase 29 family.
Protein type: Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.99.-; Transferase
Chromosomal Location of Human Ortholog: 3q12.1
Cellular Component: Golgi membrane; integral to membrane; integral to Golgi membrane
Biological Process: keratan sulfate metabolic process; glycolipid metabolic process; cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; carbohydrate metabolic process; protein modification process; pathogenesis; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification; oligosaccharide metabolic process
Research Articles on ST3GAL6
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Product Notes
The ST3GAL6 st3gal6 (Catalog #AAA716546) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 polyclonal Antibody reacts with Human,Mouse,Rat; Other species are not tested. Please decide the specificity by homology. and may cross-react with other species as described in the data sheet. AAA Biotech's ST3 beta-galactoside alpha-2, 3-sialyltransferase 6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA; Use at an assay dependent dilution. WB : 1:500-1:5000 (Recommender dilution) Positive WB detected in: Human placenta tissue, human heart tissue. Researchers should empirically determine the suitability of the ST3GAL6 st3gal6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ST3 beta-galactoside alpha-2, 3-sialyltransferase 6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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