Western Blot (WB)
(Western blot analysis of SSX-pan expression in HEK293 (A), MDAMB453 (B), SW480 (C), A549 (D) whole cell lysates.)
Rabbit anti-Human SSX-pan Polyclonal Antibody | anti-SSX1 antibody
Anti-SSX-pan Antibody
Western Blot (WB)
(Western blot analysis of SSX-pan expression in HEK293 (A), MDAMB453 (B), SW480 (C), A549 (D) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of SSX-pan expression in HEK293 (A), MDAMB453 (B), SW480 (C), A549 (D) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013]
Uniprot Description
SSX1: Could act as a modulator of transcription. A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). Belongs to the SSX family.
Protein type: Cancer Testis Antigen (CTA); Oncoprotein
Chromosomal Location of Human Ortholog: Xp11.23
Cellular Component: nucleus
Molecular Function: nucleic acid binding; transcription corepressor activity
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Disease: Sarcoma, Synovial
Research Articles on SSX1
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Product Notes
The SSX1 ssx1 (Catalog #AAA822001) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SSX-pan Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SSX-pan can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the SSX1 ssx1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SSX-pan, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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