Rabbit anti-Human SSTR5 Polyclonal Antibody | anti-SSTR5 antibody

SSTR5 (Somatostatin Receptor 5, SS-5-R) (PE)

Cat. Num. AAA6439057

• Gene Names: SSTR5; SS-5-R
• Reactivity: Human
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by affinity chromatography.
• Synonyms: SSTR5; Polyclonal Antibody; SSTR5 (Somatostatin Receptor 5; SS-5-R) (PE); anti-SSTR5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human SSTR5.
• Purity/Purification: Purified by affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
• Concentration: ~1mg/ml (varies by lot)

• Applicable Applications for anti-SSTR5 antibody: Immunohistochemistry (IHC), Western Blot (WB)
• Application Notes: IHC: 1:50-1:100; WB: 1:500-1:1000; Applications are based on unconjugated antibody.
• Immunogen: Synthetic peptide corresponding to human SSTR5.
• Conjugate: PE
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(Western blot analysis of extracts of Mouse thmus, using SSTR5 antibody.)

Product Categories/Family for anti-SSTR5 antibody

Antibodies; Receptors

NCBI and Uniprot Product Information

• NCBI GI #: 12644225
• NCBI GeneID: 6755
• UniProt Accession #: P35346; P34988; Q541E0; Q9UJI5; AAB31829
• NCBI Official Full Name: Somatostatin receptor type 5
• NCBI Official Synonym Full Names: somatostatin receptor 5
• NCBI Official Symbol: SSTR5
• NCBI Official Synonym Symbols: SS-5-R
• NCBI Protein Information: somatostatin receptor type 5; somatostatin receptor subtype 5
• UniProt Protein Name: Somatostatin receptor type 5
• Protein Family: Somatostatin receptor
• UniProt Gene Name: SSTR5
• UniProt Synonym Gene Names: SS-5-R; SS5-R; SS5R
• UniProt Entry Name: SSR5_HUMAN

NCBI Description

Somatostatin and its related peptide cortistatin exert multiple biological actions on normal and tumoral tissue targets by interacting with somatostatin receptors (SSTRs). The protein encoded by this gene is one of the SSTRs, which is a multi-pass membrane protein and belongs to the G-protein coupled receptor 1 family. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase, and different regions of this receptor molecule are required for the activation of different signaling pathways. A mutation in this gene results in somatostatin analog resistance. Alternatively spliced transcript variants have been identified in this gene.[provided by RefSeq, Feb 2010]

Uniprot Description

SSTR5: Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; GPCR, family 1; Cell cycle regulation; Receptor, GPCR; Membrane protein, integral

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: neuron projection; integral to plasma membrane; plasma membrane

Molecular Function: neuropeptide binding; somatostatin receptor activity

Biological Process: positive regulation of cytokinesis; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; synaptic transmission; G-protein coupled receptor protein signaling pathway; neuropeptide signaling pathway; glucose homeostasis; regulation of insulin secretion

Disease: Pituitary Adenoma, Growth Hormone-secreting