Western Blot (WB)
(SSSCA1 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SSSCA1 antibody detected the SSSCA1 protein (arrow).)
Rabbit anti-Human, Mouse SSSCA1 Polyclonal Antibody | anti-SSSCA1 antibody
SSSCA1, NT (SSSCA1, Sjoegren syndrome/scleroderma autoantigen 1, Autoantigen p27) (APC)
Gene Names
SSSCA1; p27
Reactivity
Human, Mouse
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
SSSCA1; Polyclonal Antibody; NT (SSSCA1; Sjoegren syndrome/scleroderma autoantigen 1; Autoantigen p27) (APC); Autoantigen p27; anti-SSSCA1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-SSSCA1 antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
SSSCA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human SSSCA1.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(SSSCA1 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SSSCA1 antibody detected the SSSCA1 protein (arrow).)
Western Blot (WB)
(SSSCA1 Antibody (N-term) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the SSSCA1 antibody detected the SSSCA1 protein (arrow).)
Western Blot (WB)
(SSSCA1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SSSCA1 antibody detected the SSSCA1 protein (arrow).)
Western Blot (WB)
(SSSCA1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the SSSCA1 antibody detected the SSSCA1 protein (arrow).)
Related Product Information for anti-SSSCA1 antibody
This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established.
Product Categories/Family for anti-SSSCA1 antibody
References
Shen, A., et al. Neurosurgery 65(1):153-159(2009). Matsuoka, S., et al. Science 316(5828):1160-1166(2007). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Suzuki, H., et al. Genome Res. 11(10):1758-1765(2001). Muro, Y., et al. Clin. Exp. Immunol. 111(2):372-376(1998).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21,474 Da
NCBI Official Full Name
Sjoegren syndrome/scleroderma autoantigen 1 isoform 1
NCBI Official Synonym Full Names
Sjogren syndrome/scleroderma autoantigen 1
NCBI Official Symbol
SSSCA1
NCBI Official Synonym Symbols
p27
NCBI Protein Information
Sjoegren syndrome/scleroderma autoantigen 1; Sjogren's syndrome/scleroderma autoantigen 1; autoantigen p27; centromeric autoantigen (27kD)
UniProt Protein Name
Sjoegren syndrome/scleroderma autoantigen 1
Protein Family
UniProt Gene Name
SSSCA1
UniProt Entry Name
SSA27_HUMAN
NCBI Description
This antigen is recognized by a subset of anti-centromere antibodies from patients with scleroderma and/or Sjogren's syndrome. Subcellular localization has not yet been established. [provided by RefSeq, Jul 2008]
Uniprot Description
SSSCA1: Might play a role in mitosis. Antigenic molecule. Could be a centromere-associated protein. May induce anti-centromere antibodies.
Chromosomal Location of Human Ortholog: 11q13.1
Molecular Function: identical protein binding; protein binding
Biological Process: mitosis; cell division
Research Articles on SSSCA1
1. Our method identified a strong relationship between p27 expression and prostate cancer recurrence.
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Product Notes
The SSSCA1 sssca1 (Catalog #AAA6351379) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SSSCA1, NT (SSSCA1, Sjoegren syndrome/scleroderma autoantigen 1, Autoantigen p27) (APC) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SSSCA1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SSSCA1 sssca1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SSSCA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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