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Western Blot (WB) (Fig.1. Western Blot analysis of extracts from Jurkat, K562 cells, using SS-56 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.)

Rabbit anti-Human SS-56 Polyclonal Antibody | anti-SS-56 antibody

SS-56 Polyclonal Antibody

Gene Names
TRIM68; SS56; GC109; SS-56; RNF137
Reactivity
Human
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SS-56; Polyclonal Antibody; SS-56 Polyclonal Antibody; Rabbit Anti-SS-56 Polyclonal Antibody; TRIM68; GC109; RNF137; SS56; E3 ubiquitin-protein ligase TRIM68; RING finger protein 137; SSA protein SS-56; Tripartite motif-containing protein 68; anti-SS-56 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
SS-56 Polyclonal Antibody detects endogenous levels of SS-56 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Liquid; PBS Containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
485
Applicable Applications for anti-SS-56 antibody
Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA)
Application Notes
WB: 1:500-1:2000
IHC-P: 1:100-1:300
ELISA: 1:40000
Immunogen
Synthesized peptide derived from the internal region of human SS-56
Preparation and Storage
Stable for one year at -20 degree C from date of shipment.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Western Blot (WB)

(Fig.1. Western Blot analysis of extracts from Jurkat, K562 cells, using SS-56 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.)

Western Blot (WB) (Fig.1. Western Blot analysis of extracts from Jurkat, K562 cells, using SS-56 Polyclonal Antibody. Secondary antibody was diluted at 1:20000.)

Immunohistochemistry (IHC)

(Fig.2. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100.)

Immunohistochemistry (IHC) (Fig.2. Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100.)
Related Product Information for anti-SS-56 antibody
TRIM68 encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM68 isoform 1
NCBI Official Synonym Full Names
tripartite motif containing 68
NCBI Official Symbol
TRIM68
NCBI Official Synonym Symbols
SS56; GC109; SS-56; RNF137
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM68
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM68
UniProt Gene Name
TRIM68
UniProt Synonym Gene Names
GC109; RNF137; SS56; SS-56
UniProt Entry Name
TRI68_HUMAN

NCBI Description

This gene encodes a member of the tripartite motif-containing protein family, whose members are characterized by a "really interesting new gene" (RING) finger domain, a zinc-binding B-box motif, and a coiled-coil region. Members of this family function as E3 ubiquitin ligases and are involved in a broad range of biological processes. This gene regulates the activation of nuclear receptors, such as androgen receptor, and has been implicated in development of prostate cancer cells, where its expression increases in response to a downregulation of microRNAs. In addition, this gene participates in viral defense regulation as a negative regulator of interferon-beta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

Research Articles on SS-56

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Product Notes

The SS-56 trim68 (Catalog #AAA9703477) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SS-56 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SS-56 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA). WB: 1:500-1:2000 IHC-P: 1:100-1:300 ELISA: 1:40000. Researchers should empirically determine the suitability of the SS-56 trim68 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SS-56, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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