Western Blot (WB)
(Host: RabbitTarget Name: SRD5A2Sample Tissue: Mouse Thymus lysatesAntibody Dilution: 1ug/ml)
Rabbit anti-Mouse SRD5A2 Polyclonal Antibody | anti-SRD5A2 antibody
SRD5A2 Antibody - middle region
Western Blot (WB)
(Host: RabbitTarget Name: SRD5A2Sample Tissue: Mouse Thymus lysatesAntibody Dilution: 1ug/ml)
Western Blot (WB)
(Host: RabbitTarget Name: SRD5A2Sample Tissue: Mouse Thymus lysatesAntibody Dilution: 1ug/ml)
NCBI and Uniprot Product Information
Uniprot Description
SRD5A2: Converts testosterone (T) into 5-alpha- dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Defects in SRD5A2 are the cause of pseudovaginal perineoscrotal hypospadias (PPSH). A form of male pseudohermaphroditism in which 46,XY males show ambiguous genitalia at birth, including perineal hypospadias and a blind perineal pouch, and develop masculinization at puberty. The name of the disorder stems from the finding of a blind-ending perineal opening resembling a vagina and a severely hypospadiac penis with the urethra opening onto the perineum. Belongs to the steroid 5-alpha reductase family.
Protein type: Lipid Metabolism - androgen and estrogen; Oxidoreductase; Membrane protein, integral; EC 1.3.1.22; Membrane protein, multi-pass
Cellular Component: cell soma; intracellular membrane-bound organelle; membrane; endoplasmic reticulum; cytoplasm; integral to membrane
Molecular Function: amide binding; oxidoreductase activity, acting on the CH-CH group of donors; cholestenone 5-alpha-reductase activity; sterol 5-alpha reductase activity; oxidoreductase activity; 3-oxo-5-alpha-steroid 4-dehydrogenase activity
Biological Process: response to organic substance; steroid metabolic process; response to peptide hormone stimulus; androgen metabolic process; male gonad development; male genitalia development; androgen biosynthetic process; lipid metabolic process; cell differentiation; sex differentiation; steroid biosynthetic process; steroid catabolic process
Research Articles on SRD5A2
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Product Notes
The SRD5A2 srd5a2 (Catalog #AAA3223686) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRD5A2 Antibody - middle region reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SRD5A2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the SRD5A2 srd5a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Synthetic peptide located within the following region: YRIPQGGLFT YVSGANFLGE IIEWMGYALA TWSVPAFAFA FFTLCFLGMQ. It is sometimes possible for the material contained within the vial of "SRD5A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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