Western Blot (WB)
(Western blot analysis SRC-1 (Phospho-Thr1179) using Jurkat whole cell lysates)
Rabbit anti-Human, Mouse SRC-1 Polyclonal Antibody | anti-SRC-1 antibody
SRC-1 (Phospho-Thr1179) Antibody
Western Blot (WB)
(Western blot analysis SRC-1 (Phospho-Thr1179) using Jurkat whole cell lysates)
Western Blot (WB)
(Western blot analysis SRC-1 (Phospho-Thr1179) using Jurkat whole cell lysates)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene acts as a transcriptional coactivator for steroid and nuclear hormone receptors. It is a member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, as well as bHLH and PAS domains. The product of this gene binds nuclear receptors directly and stimulates the transcriptional activities in a hormone-dependent fashion. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
SRC-1: a transcriptional coactivator for steroid and nuclear hormone receptors. A member of the p160/steroid receptor coactivator (SRC) family and like other family members has histone acetyltransferase activity and contains a nuclear localization signal, and bHLH and PAS domains. Phosphorylated and activated via the mitogen-activated protein kinase pathway. Three alternatively spliced isoforms have been described.
Protein type: Acetyltransferase; DNA-binding; EC 2.3.1.48; Nuclear receptor co-regulator; Oncoprotein; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 2p23
Cellular Component: nuclear chromatin; nucleoplasm
Molecular Function: enzyme binding; estrogen receptor binding; ligand-dependent nuclear receptor binding; ligand-dependent nuclear receptor transcription coactivator activity; nuclear hormone receptor binding; protein binding; protein N-terminus binding; transcription coactivator activity
Biological Process: bile acid and bile salt transport; cellular lipid metabolic process; cellular response to hormone stimulus; intracellular receptor-mediated signaling pathway; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter by galactose; positive regulation of transcription, DNA-dependent; transcription, DNA-dependent
Research Articles on SRC-1
Similar Products
Product Notes
The SRC-1 ncoa1 (Catalog #AAA9416728) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRC-1 (Phospho-Thr1179) Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SRC-1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000. Researchers should empirically determine the suitability of the SRC-1 ncoa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRC-1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
