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Western Blot (WB) (Western Blot analysis of SPSB2 in Human heart tissue and Human right lower lung tissue lysates in order using SPSB2 Rabbit pAb at dilution 1/800)

Rabbit SPSB2 Polyclonal Antibody | anti-SPSB2 antibody

SPSB2 Rabbit pAb

Gene Names
SPSB2; SSB2; GRCC9
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
SPSB2; Polyclonal Antibody; SPSB2 Rabbit pAb; splA/ryanodine receptor domain and SOCS box containing 2; SSB2; GRCC9; anti-SPSB2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
1.2mg/ml (varies by lot)
Applicable Applications for anti-SPSB2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
Fusion protein of human SPSB2
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Western Blot analysis of SPSB2 in Human heart tissue and Human right lower lung tissue lysates in order using SPSB2 Rabbit pAb at dilution 1/800)

Western Blot (WB) (Western Blot analysis of SPSB2 in Human heart tissue and Human right lower lung tissue lysates in order using SPSB2 Rabbit pAb at dilution 1/800)
Related Product Information for anti-SPSB2 antibody
This gene encodes a member of a subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal suppressor of cytokine signaling (SOCS) box. This protein plays a role in cell signaling. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,642 Da
NCBI Official Full Name
SPRY domain-containing SOCS box protein 2
NCBI Official Synonym Full Names
splA/ryanodine receptor domain and SOCS box containing 2
NCBI Official Symbol
SPSB2
NCBI Official Synonym Symbols
SSB2; GRCC9
NCBI Protein Information
SPRY domain-containing SOCS box protein 2; SPRY domain-containing SOCS box protein SSB-2; gene-rich cluster protein C9
UniProt Protein Name
SPRY domain-containing SOCS box protein 2
UniProt Gene Name
SPSB2
UniProt Synonym Gene Names
GRCC9; SSB2; SSB-2
UniProt Entry Name
SPSB2_HUMAN

NCBI Description

This gene encodes encodes a suppressor of cytokine signaling (SOCS) family member, and it belongs to the subfamily of proteins containing a central SPRY (repeats in splA and RyR) domain and a C-terminal SOCS box. This gene is present in a gene-rich cluster on chromosome 12p13 in the vicinity of the CD4 antigen and triosephosphate isomerase genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Uniprot Description

SPSB2: Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Belongs to the SPSB family.

Chromosomal Location of Human Ortholog: 12p13.31

Cellular Component: cytoplasm

Molecular Function: protein binding

Biological Process: protein ubiquitination

Research Articles on SPSB2

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Product Notes

The SPSB2 spsb2 (Catalog #AAA4760493) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPSB2 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SPSB2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SPSB2 spsb2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPSB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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