Rabbit splicing factor, arginine/serine-rich 17A Polyclonal Antibody | anti-AKAP17A antibody
Rabbit anti-human splicing factor, arginine/serine-rich 17A polyclonal Antibody
Gene Names
AKAP17A; XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155E
Reactivity
Human; Other species are not tested. Please decide the specificity by homology.
Applications
ELISA, Western Blot, Immunohistochemistry, Immunofluorescence
Purity
Antigen Affinity Purified
Synonyms
splicing factor; arginine/serine-rich 17A; Polyclonal Antibody; Rabbit anti-human splicing factor; arginine/serine-rich 17A polyclonal Antibody; SFRS17A; 721P; CCDC133; CXYorf3; DXYS155E; MGC125365; MGC125366; MGC39904; XE7; XE7Y; anti-AKAP17A antibody
Host
Rabbit
Reactivity
Human; Other species are not tested. Please decide the specificity by homology.
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
695
Applicable Applications for anti-AKAP17A antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Application Notes
ELISA: Use at an assay dependent dilution.
WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100 (Recommender dilutions)
Positive WB detected in: Human kidney tissue, human heart tissue
Positive IP detected in: Jurkat cells
Positive IHC detected in: Human pancreas cancer tissue
Positive IF detected in: HT-1080 cells
WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
IF : 1:10-1:100 (Recommender dilutions)
Positive WB detected in: Human kidney tissue, human heart tissue
Positive IP detected in: Jurkat cells
Positive IHC detected in: Human pancreas cancer tissue
Positive IF detected in: HT-1080 cells
Immunogen
Human SFRS17A
Conjugate
Non-conjugated
Storage Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-83940 / sc-83941
Preparation and Storage
Shipped at 4 degree C Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-AKAP17A antibody
Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre-mRNA splicing in a PKA-dependent manner.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
Splicing factor, arginine/serine-rich 17A
NCBI Official Synonym Full Names
A kinase (PRKA) anchor protein 17A
NCBI Official Symbol
AKAP17A
NCBI Official Synonym Symbols
XE7; 721P; XE7Y; CCDC133; CXYorf3; PRKA17A; SFRS17A; AKAP-17A; DXYS155E
NCBI Protein Information
A-kinase anchor protein 17A; pseudoautosomal gene XE7; B-lymphocyte surface antigen; protein kinase A-anchoring protein 17A; splicing factor, arginine/serine-rich 17A
UniProt Protein Name
A-kinase anchor protein 17A
Protein Family
UniProt Gene Name
AKAP17A
UniProt Synonym Gene Names
CXYorf3; DXYS155E; SFRS17A; XE7; AKAP-17A; PRKA17A
UniProt Entry Name
AK17A_HUMAN
NCBI Description
This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]
Uniprot Description
SFRS17A: Splice factor regulating alternative splice site selection for certain mRNA precursors. Mediates regulation of pre- mRNA splicing in a PKA-dependent manner. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA splicing
Chromosomal Location of Human Ortholog: Xp22.33 and Yp11.32
Cellular Component: nucleoplasm; spliceosome; cytoplasm; nuclear speck; nucleus
Molecular Function: protein binding; protein kinase A binding; nucleotide binding
Biological Process: B cell activation; regulation of transcription, DNA-dependent; regulation of RNA splicing; RNA splicing; signal transduction; mRNA processing
Research Articles on AKAP17A
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Product Notes
The AKAP17A akap17a (Catalog #AAA711914) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human splicing factor, arginine/serine-rich 17A polyclonal Antibody reacts with Human; Other species are not tested. Please decide the specificity by homology. and may cross-react with other species as described in the data sheet. AAA Biotech's splicing factor, arginine/serine-rich 17A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). ELISA: Use at an assay dependent dilution. WB : 1:500-1:5000 IP : 1:200-1:2000 IHC : 1:20-1:200 IF : 1:10-1:100 (Recommender dilutions) Positive WB detected in: Human kidney tissue, human heart tissue Positive IP detected in: Jurkat cells Positive IHC detected in: Human pancreas cancer tissue Positive IF detected in: HT-1080 cells. Researchers should empirically determine the suitability of the AKAP17A akap17a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "splicing factor, arginine/serine-rich 17A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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