Western Blot (WB)
(Western blot analysis of SPCS3 antibody (C-term) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.)
Rabbit anti-Human, Mouse SPCS3 Polyclonal Antibody | anti-SPCS3 antibody
SPCS3, CT (Signal Peptidase Complex Subunit 3, Microsomal Signal Peptidase 22/23kD Subunit, SPase 22/23kD Subunit, SPC22/23, SPC22, UNQ1841/PRO3567) (AP)
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of SPCS3 antibody (C-term) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.)
Western Blot (WB)
(Western blot analysis of SPCS3 antibody (C-term) in mouse liver tissue lysates (35ug/lane). SPCS3 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SPCS3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SPCS3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(SPCS3 Antibody (C-term) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(SPCS3 Antibody (C-term) flow cytometry analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
Uniprot Description
SPCS3: Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. Belongs to the SPCS3 family.
Protein type: Membrane protein, integral; Cofactor and Vitamin Metabolism - biotin; Protease; Amino Acid Metabolism - lysine degradation; EC 3.4.-.-
Chromosomal Location of Human Ortholog: 4q34.2
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane; signal peptidase complex
Molecular Function: peptidase activity
Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; signal peptide processing; translation; gene expression; proteolysis; regulation of insulin secretion
Similar Products
Product Notes
The SPCS3 spcs3 (Catalog #AAA6500359) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPCS3, CT (Signal Peptidase Complex Subunit 3, Microsomal Signal Peptidase 22/23kD Subunit, SPase 22/23kD Subunit, SPC22/23, SPC22, UNQ1841/PRO3567) (AP) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SPCS3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:50-1:100 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the SPCS3 spcs3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPCS3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
