Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells using SPAG5 antibody. Blue: DAPI for nuclear staining.)
Rabbit anti-Human SPAG5 Polyclonal Antibody | anti-SPAG5 antibody
SPAG5 Polyclonal Antibody
IHC: 1:50 - 1:200
IF: 1:50 - 1:100
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells using SPAG5 antibody. Blue: DAPI for nuclear staining.)
Immunofluorescence (IF)
(Immunofluorescence analysis of HeLa cells using SPAG5 antibody. Blue: DAPI for nuclear staining.)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. [provided by RefSeq, Jul 2008]
Uniprot Description
SPAG5: Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
Protein type: Cell cycle regulation
Chromosomal Location of Human Ortholog: 17q11.2
Cellular Component: kinetochore; nucleoplasm; spindle pole; cytoplasm; microtubule organizing center; midbody; nucleus
Molecular Function: protein binding
Biological Process: regulation of attachment of spindle microtubules to kinetochore; mitotic sister chromatid segregation; cell division; spindle organization and biogenesis; chromosome segregation
Research Articles on SPAG5
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Product Notes
The SPAG5 spag5 (Catalog #AAA9127092) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SPAG5 Polyclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPAG5 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF). WB: 1:500 - 1:2000 IHC: 1:50 - 1:200 IF: 1:50 - 1:100. Researchers should empirically determine the suitability of the SPAG5 spag5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPAG5, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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