Immunohistochemistry (IHC)
(Immunochemical staining of human ACRV1 in human testis with rabbit polyclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SP-10/ACRV1 Polyclonal Antibody | anti-ACRV1 antibody
Anti-SP-10/ACRV1 Antibody, Rabbit Polyclonal
Gene Names
ACRV1; SP-10; SPACA2; D11S4365
Reactivity
Human
Applications
ELISA, Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SP-10/ACRV1; Polyclonal Antibody; Anti-SP-10/ACRV1 Antibody; Rabbit Polyclonal; SP-10/ACRV1 Antibody; Rabbit PAb; Antigen Affinity Purified; acrosomal vesicle protein 1; Anti-D11S4365 Antibody; Anti-SP-10 Antibody; Anti-SPACA2 Antibody; anti-ACRV1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SP-10/ACRV1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-ACRV1 antibody
ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
ELISA: 1:5000-1:10,000
IHC-P: 1:000-1:50,000
IHC-P: 1:000-1:50,000
Immunogen
Recombinant Human SP-10/ACRV1 Protein
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with purified, recombinant Human SP-10/ACRV1 (rh SP-10/ACRV1). SP-10/ACRV1 specific IgG was purified by Human SP-10/ACRV1 affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.
Immunohistochemistry (IHC)
(Immunochemical staining of human ACRV1 in human testis with rabbit polyclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections.)
Immunohistochemistry (IHC)
(Immunochemical staining of human ACRV1 in human testis with rabbit polyclonal antibody at 1:20000 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-ACRV1 antibody
Acrosomal protein SP-1, also known as Acrosomal vesicle protein 1 and ACRV1, is a testis-specific, differentiation antigen, that arises within the acrosomal vesicle during spermatogenesis, and is associated with the acrosomal membranes and matrix of mature sperm. Regulation of cell type-specific gene transcription is central to cellular differentiation and development. During spermatogenesis, a number of testis-specific genes are expressed in a precise spatiotemporal order. The longest transcript of ACRV1/SP-1 is the most abundant, comprising 53-72% of the total acrosomal vesicle protein 1 messages; the second largest transcript comprises 15-32%; the third and the fourth largest transcripts account for 3.4-8.3% and 8.7-12.5%, respectively; and the remaining transcripts combined account for <1% of the total acrosomal vesicle protein 1 message. ACRV1/SP-1 is a testis-specific acrosomal protein that has been detected in several species including humans. It may be involved in sperm-zona binding or penetration, and it is a potential contraceptive vaccine immunogen for humans. ACRV1/SP-1 may be involved in sperm-zona binding or penetration. It is also a intra-acrosomal protein that is considered to be a vaccine candidate for immunocontraception.
References
Wright RM, et al., 1990, Biol Reprod. 42 (4): 693-701. Kurth, B.E. et al., 1993, Anat Rec. 236 (4):619-25. Golden WL, et al., 1994, Genomics.18 (2): 446-9. Foster, J.A. et al., 1994, Biol Reprod. 51 (6):1222-31. Abhyankar, M.M. et al., 2007, J Biol Chem. 282 (50): 36143-54.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9,030 Da
NCBI Official Full Name
acrosomal protein SP-10 isoform a
NCBI Official Synonym Full Names
acrosomal vesicle protein 1
NCBI Official Symbol
ACRV1
NCBI Official Synonym Symbols
SP-10; SPACA2; D11S4365
NCBI Protein Information
acrosomal protein SP-10; sperm protein 10
UniProt Protein Name
Acrosomal protein SP-10
Protein Family
UniProt Gene Name
ACRV1
UniProt Entry Name
ASPX_HUMAN
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Product Notes
The ACRV1 acrv1 (Catalog #AAA8105808) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SP-10/ACRV1 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SP-10/ACRV1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry-Paraffin (IHC-P). ELISA: 1:5000-1:10,000 IHC-P: 1:000-1:50,000. Researchers should empirically determine the suitability of the ACRV1 acrv1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SP-10/ACRV1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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