Western Blot (WB)
((0.5ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Goat SOX11 Polyclonal Antibody | anti-SOX11 antibody
Goat anti-SOX11 (aa309-323) Antibody
Western Blot: Approx 65kDa band observed in lysates of cell lines Daudi, Jurkat and MOLT4 (calculated MW of 46.7kDa according to NP_003099.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Dictor et al, Haematologica.2009 Nov;94(11): 1563-8. PMID: 19880779). Recommended concentration: 0.3-1ug/ml.
Western Blot (WB)
((0.5ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB)
((0.5ug/ml) staining of MOLT4 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
NCBI and Uniprot Product Information
NCBI Description
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The protein may function in the developing nervous system and play a role in tumorigenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
SOX11: Probably important in the developing nervous system. May also have a role in tissue modeling during development.
Protein type: DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: cytoplasm; nucleus
Molecular Function: transcription factor activity; translation factor activity, nucleic acid binding
Biological Process: embryonic digestive tract morphogenesis; embryonic skeletal morphogenesis; glial cell development; glial cell proliferation; hard palate development; kidney development; lens morphogenesis in camera-type eye; limb bud formation; negative regulation of lymphocyte proliferation; negative regulation of transcription from RNA polymerase II promoter; neural crest cell development; neural tube formation; neuron differentiation; oligodendrocyte development; positive regulation of BMP signaling pathway; positive regulation of cell proliferation; positive regulation of hormone secretion; positive regulation of neurogenesis; positive regulation of neuron differentiation; positive regulation of ossification; positive regulation of osteoblast differentiation; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transforming growth factor beta receptor signaling pathway; skeletal development; soft palate development; spinal cord development; sympathetic nervous system development; transcription from RNA polymerase II promoter; translation
Disease: Mental Retardation, Autosomal Dominant 27
Research Articles on SOX11
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Product Notes
The SOX11 sox11 (Catalog #AAA422794) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-SOX11 (aa309-323) Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Pig, Cow and may cross-react with other species as described in the data sheet. AAA Biotech's SOX11 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB). Peptide ELISA: Antibody detection limit dilution 1: 2000. Western Blot: Approx 65kDa band observed in lysates of cell lines Daudi, Jurkat and MOLT4 (calculated MW of 46.7kDa according to NP_003099.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Dictor et al, Haematologica.2009 Nov;94(11): 1563-8. PMID: 19880779). Recommended concentration: 0.3-1ug/ml. Researchers should empirically determine the suitability of the SOX11 sox11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: SRLYYSFKNI TKQHP. It is sometimes possible for the material contained within the vial of "SOX11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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