Western Blot (WB)
(Western blot analysis of SOSTDC1 expression in U87MG (A), mouse kidney (B), rat brain (C) whole cell lysates.)
Rabbit SOSTDC1 Polyclonal Antibody | anti-SOSTDC1 antibody
Anti-SOSTDC1 Antibody
Western Blot (WB)
(Western blot analysis of SOSTDC1 expression in U87MG (A), mouse kidney (B), rat brain (C) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of SOSTDC1 expression in U87MG (A), mouse kidney (B), rat brain (C) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the sclerostin family and encodes an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death. [provided by RefSeq, Jul 2008]
Uniprot Description
SOSTDC1: May be involved in the onset of endometrial receptivity for implantation/sensitization for the decidual cell reaction Enhances Wnt signaling and inhibits TGF-beta signaling. Directly antagonizes activity of BMP2, BMP4, BMP6 and BMP7 in a dose-dependent manner. Belongs to the sclerostin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 7p21.1
Cellular Component: extracellular space
Biological Process: hair follicle morphogenesis; Wnt receptor signaling pathway; pattern specification process; odontogenesis of dentine-containing teeth; negative regulation of BMP signaling pathway; negative regulation of cell fate commitment
Research Articles on SOSTDC1
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Product Notes
The SOSTDC1 sostdc1 (Catalog #AAA8308219) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SOSTDC1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SOSTDC1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the SOSTDC1 sostdc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SOSTDC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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