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Testing Data (Lane 1: Smart Protein Standard (Middle-Range) Lane 2: 50 ug Mouse spleen tissue lysate MBS623889 Secondary antibody: Goat Anti-Rabbit IgG (H&L) [HRP] Polyclonal Antibody (1:10,000))

Rabbit anti-Mouse Solute carrier family 25, member 37 Polyclonal Antibody | anti-SLC25A37 antibody

Solute carrier family 25, member 37 (HT015, MFRN, Mitochondrial iron transporter 1, Mitochondrial solute carrier protein, Mitochondria solute carrier protein, Mitoferrin-1, MSC, MSCP, PRO1278, PRO1584, PRO2217, Solute carrier family 25 member 37)

Gene Names
SLC25A37; MSC; MFRN; MSCP; HT015; MFRN1; PRO1278; PRO1584; PRO2217
Reactivity
Mouse
Applications
ELISA, Western Blot
Purity
Affinity Purified
Purified by Protein A affinity chromatography.
Synonyms
Solute carrier family 25; member 37; Polyclonal Antibody; member 37 (HT015; MFRN; Mitochondrial iron transporter 1; Mitochondrial solute carrier protein; Mitochondria solute carrier protein; Mitoferrin-1; MSC; MSCP; PRO1278; PRO1584; PRO2217; Solute carrier family 25 member 37); Anti -Solute carrier family 25; anti-SLC25A37 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes mouse Mitoferrin-1.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide, 30% glycerol.
Applicable Applications for anti-SLC25A37 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes
Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 0.25-1ug/ml
Western Blot: 1-2ug/ml
Immunogen
Synthetic peptide corresponding to YILTKRQLENRTLY of mouse Solute carrier family 25, member 37 (KLH).
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Testing Data

(Lane 1: Smart Protein Standard (Middle-Range) Lane 2: 50 ug Mouse spleen tissue lysate MBS623889 Secondary antibody: Goat Anti-Rabbit IgG (H&L) [HRP] Polyclonal Antibody (1:10,000))

Testing Data (Lane 1: Smart Protein Standard (Middle-Range) Lane 2: 50 ug Mouse spleen tissue lysate MBS623889 Secondary antibody: Goat Anti-Rabbit IgG (H&L) [HRP] Polyclonal Antibody (1:10,000))
Related Product Information for anti-SLC25A37 antibody
Mitoferrin-1 belongs to the mitochondrial carrier family. It specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. Mitoferrin-1, also known as mitochondrial iron transporter 1, is found on the inner mitochondrial membrane. It is member 27 of solute carrier family 25.
Product Categories/Family for anti-SLC25A37 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
37,323 Da
NCBI Official Full Name
Solute carrier family 25, member 37
NCBI Official Synonym Full Names
solute carrier family 25, member 37
NCBI Official Symbol
SLC25A37
NCBI Official Synonym Symbols
MSC; MFRN; MSCP; HT015; MFRN1; PRO1278; PRO1584; PRO2217
NCBI Protein Information
mitoferrin-1; OTTHUMP00000225191; OTTHUMP00000225195; predicted protein of HQ2217; mitochondrial iron transporter 1; mitochondrial solute carrier protein
UniProt Protein Name
Mitoferrin-1
Protein Family
UniProt Gene Name
SLC25A37
UniProt Synonym Gene Names
MFRN; MSCP
UniProt Entry Name
MFRN1_HUMAN

NCBI Description

SLC25A37 is a solute carrier localized in the mitochondrial inner membrane. It functions as an essential iron importer for the synthesis of mitochondrial heme and iron-sulfur clusters (summary by Chen et al., 2009 [PubMed 19805291]).[supplied by OMIM]

Uniprot Description

SLC25A37: Mitochondrial iron transporter that specifically mediates iron uptake in developing erythroid cells, thereby playing an essential role in heme biosynthesis. The iron delivered into the mitochondria, presumably as Fe(2+), is then probably delivered to ferrochelatase to catalyze Fe(2+) incorporation into protoprophyrin IX to make heme. Belongs to the mitochondrial carrier family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Mitochondrial; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8p21.2

Cellular Component: mitochondrial inner membrane; integral to membrane

Molecular Function: iron ion transmembrane transporter activity

Biological Process: iron ion homeostasis; mitochondrial iron ion transport

Research Articles on SLC25A37

Similar Products

Product Notes

The SLC25A37 slc25a37 (Catalog #AAA623889) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Solute carrier family 25, member 37 (HT015, MFRN, Mitochondrial iron transporter 1, Mitochondrial solute carrier protein, Mitochondria solute carrier protein, Mitoferrin-1, MSC, MSCP, PRO1278, PRO1584, PRO2217, Solute carrier family 25 member 37) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Solute carrier family 25, member 37 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB). Suitable for use in ELISA and Western Blot. Dilution: ELISA: 0.25-1ug/ml Western Blot: 1-2ug/ml. Researchers should empirically determine the suitability of the SLC25A37 slc25a37 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Solute carrier family 25, member 37, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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